PMID- 27437235
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160720
LR  - 20200930
IS  - 2249-782X (Print)
IS  - 0973-709X (Electronic)
IS  - 0973-709X (Linking)
VI  - 10
IP  - 5
DP  - 2016 May
TI  - Unusual Presentation of Light Chain Deposition Disease: A Case Report.
PG  - ED08-9
LID - 10.7860/JCDR/2016/18358.7762 [doi]
AB  - Light Chain Deposition Disease (LCDD) is a rare disease characterized by 
      deposition of monoclonal non-amyloid light chains in multiple organs. We report 
      an unusual histologic manifestation of LCDD in a 55-year-old female patient, who 
      presented with nephrotic syndrome and an increased serum creatinine. This case of 
      LCDD had features of cast nephropathy on biopsy which is diagnostic of myeloma 
      kidney, when the patient was clinically asymptomatic. Serum electrophoresis 
      showed no abnormal band. There was no other evidence of a B-cell clonal disorder 
      or amyloidosis. Following chemotherapy, improvement in renal function correlated 
      with a reduction in circulating light-chain levels.
FAU - Arora, Disha
AU  - Arora D
AD  - Senior Resident, Department of Pathology, Safdarjung Hospital , New Delhi, India 
      .
FAU - Uppal, Mayank
AU  - Uppal M
AD  - Ex- Senior Resident, Department of Medicine, Safdarjung Hospital , New Delhi, 
      India .
FAU - Amitabh, Vindu
AU  - Amitabh V
AD  - Head of Department, Department of Nephrology, Safdarjung Hospital , New Delhi, 
      India .
FAU - Agrawal, Usha
AU  - Agrawal U
AD  - Scientist E, National Institute of Pathology, Safdarjung Hospital Campus , New 
      Delhi, India .
LA  - eng
PT  - Case Reports
DEP - 20160501
PL  - India
TA  - J Clin Diagn Res
JT  - Journal of clinical and diagnostic research : JCDR
JID - 101488993
PMC - PMC4948411
OTO - NOTNLM
OT  - Cast nephropathy
OT  - Myeloma kidney
OT  - Nephrotic syndrome
EDAT- 2016/07/21 06:00
MHDA- 2016/07/21 06:01
PMCR- 2016/07/01
CRDT- 2016/07/21 06:00
PHST- 2015/12/15 00:00 [received]
PHST- 2016/02/29 00:00 [accepted]
PHST- 2016/07/21 06:00 [entrez]
PHST- 2016/07/21 06:00 [pubmed]
PHST- 2016/07/21 06:01 [medline]
PHST- 2016/07/01 00:00 [pmc-release]
AID - 10.7860/JCDR/2016/18358.7762 [doi]
PST - ppublish
SO  - J Clin Diagn Res. 2016 May;10(5):ED08-9. doi: 10.7860/JCDR/2016/18358.7762. Epub 
      2016 May 1.