PMID- 27445077
OWN - NLM
STAT- MEDLINE
DCOM- 20170531
LR  - 20181202
IS  - 1724-6016 (Electronic)
IS  - 1120-6721 (Linking)
VI  - 27
IP  - 3
DP  - 2017 May 11
TI  - Retinal nerve fiber and optic disc morphology using spectral-domain optical 
      coherence tomography in scleroderma patients.
PG  - 281-284
LID - 10.5301/ejo.5000827 [doi]
AB  - PURPOSE: To evaluate the optic nerve head parameters and peripapillary retinal 
      nerve fiber layer using spectral-domain optical coherence tomography (SD-OCT) in 
      a systemic sclerosis (SSc) cohort and age-matched controls to determine whether 
      SSc patients have an increased risk of normal-tension glaucoma (NTG). METHODS: We 
      examined 30 patients (3 male, 27 female) with SSc and 28 age- and sex-matched 
      controls. Retinal nerve fiber and optic disc morphology were evaluated using 
      Cirrus SD-OCT. RESULTS: Optic disc morphology measurements including disc area, 
      rim area, average and vertical cup/disc (C/D) ratio, and cup volume were not 
      significantly different between the study groups. The average and 4-quadrant 
      retinal nerve fiber layer (RNFL) measurements of the C/D >0.3 subgroups were not 
      significantly different in the patients and controls. These values were also 
      similar for the C/D >0.5 subgroups except that the average inferior quadrant RNFL 
      thickness of the right eyes in the patient subgroup was significantly thinner 
      than in the control subgroup (p<0.05). CONCLUSIONS: Our SSc cohort had relatively 
      shorter disease duration but increased prevalence of early glaucomatous damage 
      signs. Our findings indicate that SSc is a risk factor for developing 
      normal-tension glaucoma. Further studies combined with visual field evaluation 
      are necessary to identify the long-term glaucomatous effects of SSc.
FAU - Sahin-Atik, Sevinc
AU  - Sahin-Atik S
AD  -  Department of Ophthalmology, Ataturk Teaching and Research Hospital, Yesilyurt, 
      Izmir - Turkey.
FAU - Koc, Feray
AU  - Koc F
AD  -  Department of Ophthalmology, Ataturk Teaching and Research Hospital, Yesilyurt, 
      Izmir - Turkey.
FAU - Akin-Sari, Sirin
AU  - Akin-Sari S
AD  -  Department of Internal Medicine, Bigadic Public Hospital, Balikesir - Turkey.
FAU - Ozmen, Mustafa
AU  - Ozmen M
AD  -  Department of Internal Medicine, Division of Rheumatology, Ataturk Teaching and 
      Research Hospital, Yesilyurt, Izmir - Turkey.
LA  - eng
PT  - Journal Article
DEP - 20160716
PL  - United States
TA  - Eur J Ophthalmol
JT  - European journal of ophthalmology
JID - 9110772
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - Low Tension Glaucoma/*diagnosis/etiology
MH  - Male
MH  - Middle Aged
MH  - Nerve Fibers/*physiology
MH  - Optic Disk/*pathology
MH  - Reproducibility of Results
MH  - Retinal Ganglion Cells/*pathology
MH  - Scleroderma, Systemic/*complications/diagnosis
MH  - Tomography, Optical Coherence/*methods
MH  - Visual Fields
EDAT- 2016/10/30 06:00
MHDA- 2017/06/01 06:00
CRDT- 2016/07/23 06:00
PHST- 2016/06/14 00:00 [accepted]
PHST- 2016/10/30 06:00 [pubmed]
PHST- 2017/06/01 06:00 [medline]
PHST- 2016/07/23 06:00 [entrez]
AID - D1A0B450-F43B-4977-BBCA-BE615ABB3A91 [pii]
AID - 10.5301/ejo.5000827 [doi]
PST - ppublish
SO  - Eur J Ophthalmol. 2017 May 11;27(3):281-284. doi: 10.5301/ejo.5000827. Epub 2016 
      Jul 16.