PMID- 27445476
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160722
LR  - 20220311
IS  - 1176-6328 (Print)
IS  - 1178-2021 (Electronic)
IS  - 1176-6328 (Linking)
VI  - 12
DP  - 2016
TI  - Measuring illness insight in patients with alcohol-related cognitive dysfunction 
      using the Q8 questionnaire: a validation study.
PG  - 1609-15
LID - 10.2147/NDT.S104442 [doi]
AB  - AIM: Impaired illness insight may hamper treatment outcome in patients with 
      alcohol-related cognitive deficits. In this study, a short questionnaire for the 
      assessment of illness insight (eg, the Q8) was investigated in patients with 
      Korsakoff's syndrome (KS) and in alcohol use disorder (AUD) patients with mild 
      neurocognitive deficits. METHODS: First, reliability coefficients were computed 
      and internal structure was investigated. Then, comparisons were made between 
      patients with KS and patients with AUD. Furthermore, correlations with the 
      Dysexecutive Questionnaire (DEX) were investigated. Finally, Q8 total scores were 
      correlated with neuropsychological tests for processing speed, memory, and 
      executive function. RESULTS: Internal consistency of the Q8 was acceptable (ie, 
      Cronbach's alpha =0.73). The Q8 items represent one factor, and scores differ 
      significantly between AUD and KS patients. The Q8 total score, related to the DEX 
      discrepancy score and scores on neuropsychological tests as was hypothesized, 
      indicates that a higher degree of illness insight is associated with a higher 
      level of cognitive functioning. CONCLUSION: The Q8 is a short, valid, and 
      easy-to-administer questionnaire to reliably assess illness insight in patients 
      with moderate-to-severe alcohol-related cognitive dysfunction.
FAU - Walvoort, Serge Jw
AU  - Walvoort SJ
AD  - Centre of Excellence for Korsakoff and Alcohol-Related Cognitive Disorders, 
      Vincent van Gogh Institute for Psychiatry, Venray; Donders Institute for Brain, 
      Cognition and Behaviour; Behavioural Science Institute, Radboud University, 
      Nijmegen.
FAU - van der Heijden, Paul T
AU  - van der Heijden PT
AD  - Behavioural Science Institute, Radboud University, Nijmegen; Reinier van Arkel 
      Mental Health Institute, 's-Hertogenbosch.
FAU - Kessels, Roy Pc
AU  - Kessels RP
AD  - Centre of Excellence for Korsakoff and Alcohol-Related Cognitive Disorders, 
      Vincent van Gogh Institute for Psychiatry, Venray; Donders Institute for Brain, 
      Cognition and Behaviour; Department of Medical Psychology, Radboud University 
      Medical Center, Nijmegen.
FAU - Egger, Jos Im
AU  - Egger JI
AD  - Centre of Excellence for Korsakoff and Alcohol-Related Cognitive Disorders, 
      Vincent van Gogh Institute for Psychiatry, Venray; Donders Institute for Brain, 
      Cognition and Behaviour; Behavioural Science Institute, Radboud University, 
      Nijmegen; Centre of Excellence for Neuropsychiatry, Vincent van Gogh Institute 
      for Psychiatry, Venray, the Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20160701
PL  - New Zealand
TA  - Neuropsychiatr Dis Treat
JT  - Neuropsychiatric disease and treatment
JID - 101240304
PMC - PMC4936806
OTO - NOTNLM
OT  - Korsakoff's syndrome
OT  - alcohol use disorder
OT  - anosognosia
OT  - cognition
OT  - illness insight
OT  - neuropsychological assessment
EDAT- 2016/07/23 06:00
MHDA- 2016/07/23 06:01
PMCR- 2016/07/01
CRDT- 2016/07/23 06:00
PHST- 2016/07/23 06:00 [entrez]
PHST- 2016/07/23 06:00 [pubmed]
PHST- 2016/07/23 06:01 [medline]
PHST- 2016/07/01 00:00 [pmc-release]
AID - ndt-12-1609 [pii]
AID - 10.2147/NDT.S104442 [doi]
PST - epublish
SO  - Neuropsychiatr Dis Treat. 2016 Jul 1;12:1609-15. doi: 10.2147/NDT.S104442. 
      eCollection 2016.