PMID- 27453982 OWN - NLM STAT- MEDLINE DCOM- 20170726 LR - 20181202 IS - 1471-2105 (Electronic) IS - 1471-2105 (Linking) VI - 17 Suppl 9 IP - Suppl 9 DP - 2016 Jul 19 TI - Integrating unified medical language system and association mining techniques into relevance feedback for biomedical literature search. PG - 264 LID - 10.1186/s12859-016-1129-z [doi] LID - 264 AB - BACKGROUND: Finding highly relevant articles from biomedical databases is challenging not only because it is often difficult to accurately express a user's underlying intention through keywords but also because a keyword-based query normally returns a long list of hits with many citations being unwanted by the user. This paper proposes a novel biomedical literature search system, called BiomedSearch, which supports complex queries and relevance feedback. METHODS: The system employed association mining techniques to build a k-profile representing a user's relevance feedback. More specifically, we developed a weighted interest measure and an association mining algorithm to find the strength of association between a query and each concept in the article(s) selected by the user as feedback. The top concepts were utilized to form a k-profile used for the next-round search. BiomedSearch relies on Unified Medical Language System (UMLS) knowledge sources to map text files to standard biomedical concepts. It was designed to support queries with any levels of complexity. RESULTS: A prototype of BiomedSearch software was made and it was preliminarily evaluated using the Genomics data from TREC (Text Retrieval Conference) 2006 Genomics Track. Initial experiment results indicated that BiomedSearch increased the mean average precision (MAP) for a set of queries. CONCLUSIONS: With UMLS and association mining techniques, BiomedSearch can effectively utilize users' relevance feedback to improve the performance of biomedical literature search. FAU - Ji, Yanqing AU - Ji Y AD - Department of Electrical and Computer Engineering, Gonzaga University, Spokane, WA, USA. ji@gonzaga.edu. FAU - Ying, Hao AU - Ying H AD - Department of Electrical and Computer Engineering, Wayne State University, Detroit, MI, USA. FAU - Tran, John AU - Tran J AD - Frontier Behavioral Health, Spokane, WA, USA. FAU - Dews, Peter AU - Dews P AD - Department of Medicine, St. Mary Mercy Hospital, Livonia, MI, USA. FAU - Massanari, R Michael AU - Massanari RM AD - Research for The Critical Junctures Institute, Bellingham, WA, USA. LA - eng PT - Journal Article DEP - 20160719 PL - England TA - BMC Bioinformatics JT - BMC bioinformatics JID - 100965194 SB - IM MH - Algorithms MH - Data Mining/*methods MH - Feedback MH - Genomics MH - Humans MH - Medicine in Literature MH - Search Engine/*methods MH - Software MH - Unified Medical Language System PMC - PMC4959361 OTO - NOTNLM OT - Association mining OT - Biomedical literature search OT - Relevance feedback OT - UMLS EDAT- 2016/07/28 06:00 MHDA- 2017/07/27 06:00 PMCR- 2016/07/19 CRDT- 2016/07/26 06:00 PHST- 2016/07/26 06:00 [entrez] PHST- 2016/07/28 06:00 [pubmed] PHST- 2017/07/27 06:00 [medline] PHST- 2016/07/19 00:00 [pmc-release] AID - 10.1186/s12859-016-1129-z [pii] AID - 1129 [pii] AID - 10.1186/s12859-016-1129-z [doi] PST - epublish SO - BMC Bioinformatics. 2016 Jul 19;17 Suppl 9(Suppl 9):264. doi: 10.1186/s12859-016-1129-z.