PMID- 27457830
OWN - NLM
STAT- MEDLINE
DCOM- 20170411
LR  - 20201218
IS  - 1552-6259 (Electronic)
IS  - 0003-4975 (Linking)
VI  - 102
IP  - 6
DP  - 2016 Dec
TI  - Effect of Aortic Valve Replacement on Aortic Root Dilatation Rate in Patients 
      With Bicuspid and Tricuspid Aortic Valves.
PG  - 1981-1987
LID - S0003-4975(16)30524-0 [pii]
LID - 10.1016/j.athoracsur.2016.05.038 [doi]
AB  - BACKGROUND: It remains unclear whether aortic valve replacement (AVR) has an 
      effect on the aortic root dilatation rate in patients with bicuspid aortic valve 
      (BAV) and tricuspid aortic valve (TAV). The present study evaluated the pre- and 
      postoperative annual aortic root dilatation rates in BAV and TAV. METHODS: A 
      total of 93 patients (67 +/- 11 years; 71% men) who underwent AVR between 2003 and 
      2013 and had at least 2 pre- and postoperative echocardiographic studies 1 year 
      or more apart were included in this retrospective observational study. The sinus 
      of Valsalva (SOV), sinotubular junction (STJ) and ascending aorta (AAo) were 
      measured in the parasternal long-axis view. RESULTS: Patients with BAV (n = 22) 
      were significantly younger and had less coronary artery disease than patients 
      with TAV (n = 71). At all points in time, the aortic root diameters were larger 
      in BAV compared with TAV. Preoperatively, the STJ and AAo grew significantly 
      faster in BAV compared with TAV (STJ, 0.27 versus 0.04 mm/y; p = 0.021; AAo, 0.42 
      versus 0.15 mm/y; p = 0.019). After operation, there were no significant 
      differences in aortic root dilatation rates between BAV and TAV (SOV, -0.01 
      versus 0.15 mm/y; p = 0.096; STJ, 0.08 versus 0.05 mm/y; p = 0.676; AAo, 0.28 
      versus 0.35 mm/y; p = 0.745). CONCLUSIONS: The annual aortic root dilatation 
      rates were significantly higher in BAV compared with TAV before AVR. However, 
      after AVR, aortic root dilatation rates were similar in BAV and TAV, suggesting 
      an important role of hemodynamics on aortic root dilatation in BAV.
CI  - Copyright (c) 2016 The Society of Thoracic Surgeons. Published by Elsevier Inc. All 
      rights reserved.
FAU - Regeer, Madelien V
AU  - Regeer MV
AD  - Department of Cardiology, Heart Lung Center Leiden, Leiden University Medical 
      Center, Leiden, the Netherlands.
FAU - Versteegh, Michel I M
AU  - Versteegh MI
AD  - Department of Cardio-Thoracic Surgery, Heart Lung Center Leiden, Leiden 
      University Medical Center, Leiden, the Netherlands.
FAU - Klautz, Robert J M
AU  - Klautz RJ
AD  - Department of Cardio-Thoracic Surgery, Heart Lung Center Leiden, Leiden 
      University Medical Center, Leiden, the Netherlands.
FAU - Schalij, Martin J
AU  - Schalij MJ
AD  - Department of Cardiology, Heart Lung Center Leiden, Leiden University Medical 
      Center, Leiden, the Netherlands.
FAU - Bax, Jeroen J
AU  - Bax JJ
AD  - Department of Cardiology, Heart Lung Center Leiden, Leiden University Medical 
      Center, Leiden, the Netherlands.
FAU - Marsan, Nina Ajmone
AU  - Marsan NA
AD  - Department of Cardiology, Heart Lung Center Leiden, Leiden University Medical 
      Center, Leiden, the Netherlands.
FAU - Delgado, Victoria
AU  - Delgado V
AD  - Department of Cardiology, Heart Lung Center Leiden, Leiden University Medical 
      Center, Leiden, the Netherlands. Electronic address: v.delgado@lumc.nl.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20160722
PL  - Netherlands
TA  - Ann Thorac Surg
JT  - The Annals of thoracic surgery
JID - 15030100R
SB  - IM
MH  - Aged
MH  - Anthropometry
MH  - Aorta/diagnostic imaging/*pathology
MH  - Aortic Diseases/diagnostic imaging/*etiology
MH  - Aortic Valve/*abnormalities/diagnostic imaging/physiopathology/*surgery
MH  - Aortic Valve Insufficiency/complications/diagnosis/physiopathology/*surgery
MH  - Bicuspid Aortic Valve Disease
MH  - Dilatation, Pathologic/diagnostic imaging/*etiology
MH  - Disease Progression
MH  - Echocardiography
MH  - Female
MH  - Heart Valve Diseases/diagnostic imaging/physiopathology/*surgery
MH  - *Heart Valve Prosthesis Implantation
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/diagnostic imaging/*etiology
MH  - Reoperation
MH  - Sinus of Valsalva/diagnostic imaging/*pathology
EDAT- 2016/07/28 06:00
MHDA- 2017/04/12 06:00
CRDT- 2016/07/27 06:00
PHST- 2015/08/26 00:00 [received]
PHST- 2016/04/07 00:00 [revised]
PHST- 2016/05/09 00:00 [accepted]
PHST- 2016/07/28 06:00 [pubmed]
PHST- 2017/04/12 06:00 [medline]
PHST- 2016/07/27 06:00 [entrez]
AID - S0003-4975(16)30524-0 [pii]
AID - 10.1016/j.athoracsur.2016.05.038 [doi]
PST - ppublish
SO  - Ann Thorac Surg. 2016 Dec;102(6):1981-1987. doi: 
      10.1016/j.athoracsur.2016.05.038. Epub 2016 Jul 22.