PMID- 27463621 OWN - NLM STAT- MEDLINE DCOM- 20170424 LR - 20170817 IS - 1678-2925 (Electronic) IS - 0004-2749 (Linking) VI - 79 IP - 3 DP - 2016 May-Jun TI - Effect of macular hole volume on postoperative central macular thickness. PG - 137-42 LID - S0004-27492016000300002 [pii] LID - 10.5935/0004-2749.20160043 [doi] AB - PURPOSE: To evaluate the association between macular hole volume (MHV) and postoperative central macular thickness (CMT) using spectral-domain optical coherence tomography (SD-OCT). METHODS: Thirty-three eyes of 30 patients with a large full-thickness idiopathic macular hole with or without vitreomacular traction who underwent surgical intervention were included in this cross-sectional study. Complete ophthalmological examination, including SD-OCT, was performed for all participants during the pre- and postoperative visits. MHV was preoperatively measured using SD-OCT, which captured the widest cross-sectional image of the hole. For normal distribution analysis of the data, the Kolmogorov-Smirnov test was performed, and for statistical analyses, chi-square, Student's t-test, Mann-Whitney U test, and Pearson's correlation coefficient test were performed. RESULTS: Mean preoperative best-corrected visual acuity (BCVA) and MHV were found to be 0.99 +/- 0.36 (range, 0.3-2.0) logMAR and 0.139 +/- 0.076 (range, 0.004-0.318) mm3, respectively. Mean follow-up was 16.3 +/- 14.3 (range, 3-50) months. No statistical correlations were found between MHV and postoperative BCVA (p=0.588) and between MHV and disease recurrence (p=0.544). A weak negative correlation existed between MHV and final CMT scores (p=0.04, r=-0.383). CONCLUSIONS: Greater MHV was found to be weakly associated with lower postoperative CMT scores. FAU - Ozturk, Taylan AU - Ozturk T AD - Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey. FAU - Karahan, Eyyup AU - Karahan E AD - Department of Ophthalmology, Sifa University, Izmir, Turkey. FAU - Er, Duygu AU - Er D AD - Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey. FAU - Kaya, Mahmut AU - Kaya M AD - Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey. FAU - Kocak, Nilufer AU - Kocak N AD - Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey. FAU - Kaynak, Suleyman AU - Kaynak S AD - Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey. LA - eng PT - Journal Article PL - Brazil TA - Arq Bras Oftalmol JT - Arquivos brasileiros de oftalmologia JID - 0400645 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Anatomy, Cross-Sectional MH - Cross-Sectional Studies MH - Female MH - Humans MH - Intraocular Pressure MH - Macula Lutea/*pathology/*surgery MH - Male MH - Middle Aged MH - Organ Size MH - Postoperative Period MH - Preoperative Period MH - Reference Values MH - Retinal Perforations/*pathology/*surgery MH - Statistics, Nonparametric MH - Time Factors MH - Tomography, Optical Coherence/methods MH - Treatment Outcome MH - Visual Acuity MH - Young Adult EDAT- 2016/07/28 06:00 MHDA- 2017/04/25 06:00 CRDT- 2016/07/28 06:00 PHST- 2016/01/23 00:00 [received] PHST- 2016/02/11 00:00 [accepted] PHST- 2016/07/28 06:00 [entrez] PHST- 2016/07/28 06:00 [pubmed] PHST- 2017/04/25 06:00 [medline] AID - S0004-27492016000300002 [pii] AID - 10.5935/0004-2749.20160043 [doi] PST - ppublish SO - Arq Bras Oftalmol. 2016 May-Jun;79(3):137-42. doi: 10.5935/0004-2749.20160043.