PMID- 27465298
OWN - NLM
STAT- MEDLINE
DCOM- 20200514
LR  - 20200514
IS  - 1549-8425 (Electronic)
IS  - 1549-8417 (Print)
IS  - 1549-8417 (Linking)
VI  - 15
IP  - 3
DP  - 2019 Sep
TI  - Epidemiology of Adverse Events and Medical Errors in the Care of Cardiology 
      Patients.
PG  - 251-256
LID - 10.1097/PTS.0000000000000291 [doi]
AB  - OBJECTIVES: There have been epidemiological studies of adverse events (AEs) among 
      general patients but those of patients cared by cardiologist are not well 
      scrutinized. We investigated the occurrence of AEs and medical errors (MEs) among 
      adult patients with cardiology in Japan. METHODS: We conducted a cross-sectional 
      study of adult outpatients at a Japanese teaching hospital from February through 
      November 2006. We measured AE and ME incidents from patient report, which were 
      verified by medical records, laboratory data, incident reports, and prescription 
      queries. Two independent physicians reviewed the incidents to determine whether 
      they were AEs or MEs and to assess severity and symptoms. RESULTS: We identified 
      144 AEs and 30 MEs (16.3 and 3.9 per 100 patients, respectively). Of the 144 AEs, 
      99 were solely adverse drug events (ADEs), 20 were solely non-ADEs, and the 
      remaining 25 were both causes. The most frequent symptoms of ADEs were skin and 
      allergic reactions due to medication. The most frequent symptoms of non-ADEs were 
      bleeding due to therapeutic interventions. Among AEs, 12% was life threatening. 
      Life-threatening AEs were 25% of non-ADEs and 5% of ADEs (P = 0.0003). Among the 
      30 MEs, 21MEs (70%) were associated with drugs. CONCLUSIONS: Adverse events were 
      common among cardiology patients. Adverse drug events were the most frequent AEs, 
      and non-ADEs were more critical than ADEs. Such data should be recognized among 
      practicing physicians to improve the patients' outcomes.
FAU - Ohta, Yoshinori
AU  - Ohta Y
AD  - From the Division of General Internal Medicine, Hyogo College of Medicine, Hyogo, 
      Japan.
FAU - Miki, Izumi
AU  - Miki I
AD  - National Cancer Hospital East, Chiba, Japan.
FAU - Kimura, Takeshi
AU  - Kimura T
AD  - Department of Cardiovascular Medicine, Kyoto University Graduate School of 
      Medicine, Kyoto, Japan.
FAU - Abe, Mitsuru
AU  - Abe M
AD  - Department of Cardiology, National Hospital Organization Kyoto Medical Center, 
      Kyoto, Japan.
FAU - Sakuma, Mio
AU  - Sakuma M
AD  - Department of Clinical Epidemiology, Hyogo College of Medicine, Hyogo, Japan.
FAU - Koike, Kaoru
AU  - Koike K
AD  - Department of Primary Care and Emergency Medicine, Kyoto University Graduate 
      School of Medicine, Kyoto, Japan.
FAU - Morimoto, Takeshi
AU  - Morimoto T
AD  - Department of Clinical Epidemiology, Hyogo College of Medicine, Hyogo, Japan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Patient Saf
JT  - Journal of patient safety
JID - 101233393
SB  - IM
MH  - Aged
MH  - Cardiology/*standards
MH  - Cross-Sectional Studies
MH  - Drug-Related Side Effects and Adverse Reactions/*epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Medical Errors/*trends
PMC - PMC6727907
COIS- The authors disclose no conflict of interest.
EDAT- 2016/11/05 06:00
MHDA- 2020/05/15 06:00
PMCR- 2019/09/05
CRDT- 2016/07/29 06:00
PHST- 2016/11/05 06:00 [pubmed]
PHST- 2020/05/15 06:00 [medline]
PHST- 2016/07/29 06:00 [entrez]
PHST- 2019/09/05 00:00 [pmc-release]
AID - PTS50109 [pii]
AID - 10.1097/PTS.0000000000000291 [doi]
PST - ppublish
SO  - J Patient Saf. 2019 Sep;15(3):251-256. doi: 10.1097/PTS.0000000000000291.