PMID- 27469466
OWN - NLM
STAT- MEDLINE
DCOM- 20170825
LR  - 20220317
IS  - 1865-8652 (Electronic)
IS  - 0741-238X (Linking)
VI  - 33
IP  - 10
DP  - 2016 Oct
TI  - Reliability and Responsiveness of NutriQoL((R)) Questionnaire.
PG  - 1728-1739
AB  - INTRODUCTION: NutriQoL((R)) (Nestle Health Science, Vevay, Switzerland) is a 
      questionnaire developed to assess the health-related quality-of-life (HRQoL) of 
      patients with home enteral nutrition (HEN) irrespective of their underlying 
      condition and route of administration. The aim of this work is assessing the 
      questionnaire's reliability and responsiveness to change. METHODS: Two cohorts of 
      patients with HEN and their primary caregivers were enrolled to assess 
      reliability and responsiveness, respectively. All participants had to be 18 years 
      of age or older, without mental deterioration (</=3 or 4 errors in the Pfeiffer's 
      test) and with sufficient functional status (>40 points on Karnovsky's 
      performance status scale). When the patients' ability to respond to the 
      questionnaire was impaired due to underlying disease, their caregivers answered 
      on their behalf. NutriQoL was administered in two and three visits to reliability 
      and responsiveness cohorts, respectively. Test-retest reliability and internal 
      consistency were assessed by the intra-class correlation coefficient (ICC) and 
      the Cronbach's alpha, respectively. Responsiveness was evaluated by standardized 
      effect size and standardized response mean between basal visit and third visit. 
      Finally, the minimal clinically important difference (MCID) was estimated. 
      RESULTS: A total of 54 and 86 participants were recruited to the reliability and 
      responsiveness cohort, respectively. Thirty-five caregivers were selected to 
      assess the inter-observer reliability. ICC values confirmed the good 
      reproducibility level (ICC >0.75) of the questionnaire in both "physical 
      functioning and activities of daily living" and "social life" domains and total 
      score. The assessment of internal consistency in both domains of the 
      questionnaire showed good internal consistency in visit 2. ICC showed the 
      excellent agreement level between caregiver and patient in the global NutriQoL 
      score. Finally, patients classified as having a minimal change in their health 
      reported a mean (standard deviation) MCID in NutriQoL score of 0.63 (11.51). 
      CONCLUSION: NutriQoL is a reliable and unique instrument to measure the HRQoL in 
      HEN patients. NutriQoL detects changes in the health status of the patient. 
      Nevertheless, further research is needed to determine the full extent of the 
      questionnaire responsiveness.
FAU - Cuerda, Maria Cristina
AU  - Cuerda MC
AD  - Hospital General Universitario Gregorio Maranon, Madrid, Spain.
FAU - Apezetxea, Antonio
AU  - Apezetxea A
AD  - Organizacion Sanitaria Integrada Bilbao Basurto, Bilbai, Spain.
FAU - Carrillo, Lourdes
AU  - Carrillo L
AD  - Centro de Salud Victoria de Acentejo, Santa Cruz de Tenerife, Spain.
FAU - Casanueva, Felipe
AU  - Casanueva F
AD  - Hospital Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
FAU - Cuesta, Federico
AU  - Cuesta F
AD  - Hospital Clinico San Carlos, Madrid, Spain.
FAU - Irles, Jose Antonio
AU  - Irles JA
AD  - Hospital Universitario Nuestra Senora de Valme, Sevilla, Spain.
FAU - Virgili, Maria Nuria
AU  - Virgili MN
AD  - Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
FAU - Layola, Miquel
AU  - Layola M
AD  - Nestle Health Science, Barcelona, Spain.
FAU - Lizan, Luis
AU  - Lizan L
AD  - Outcomes'10, Universitat Jaume I, Castellon, Spain. lizan@outcomes10.com.
AD  - Department of Medicine, Universitat Jaume I, Castellon, Spain. 
      lizan@outcomes10.com.
LA  - eng
PT  - Journal Article
DEP - 20160728
PL  - United States
TA  - Adv Ther
JT  - Advances in therapy
JID - 8611864
MH  - Activities of Daily Living
MH  - Adult
MH  - Aged
MH  - Caregivers
MH  - *Enteral Nutrition/methods/psychology
MH  - Female
MH  - *Home Care Services
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Quality of Life
MH  - Reproducibility of Results
MH  - Surveys and Questionnaires
MH  - Switzerland
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Gastroenterology
OT  - Health-related quality-of-life
OT  - Home enteral nutrition
OT  - Reliability
OT  - Responsiveness
EDAT- 2016/07/30 06:00
MHDA- 2017/08/26 06:00
CRDT- 2016/07/30 06:00
PHST- 2016/05/17 00:00 [received]
PHST- 2016/07/30 06:00 [pubmed]
PHST- 2017/08/26 06:00 [medline]
PHST- 2016/07/30 06:00 [entrez]
AID - 10.1007/s12325-016-0384-8 [pii]
AID - 10.1007/s12325-016-0384-8 [doi]
PST - ppublish
SO  - Adv Ther. 2016 Oct;33(10):1728-1739. doi: 10.1007/s12325-016-0384-8. Epub 2016 
      Jul 28.