PMID- 27469932
OWN - NLM
STAT- MEDLINE
DCOM- 20170331
LR  - 20170331
IS  - 1525-1470 (Electronic)
IS  - 0736-8046 (Linking)
VI  - 33
IP  - 5
DP  - 2016 Sep
TI  - Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome: An Uncommon Member of the Ectodermal 
      Dysplasias.
PG  - e322-6
LID - 10.1111/pde.12938 [doi]
AB  - Acro-dermato-ungual-lacrimal-tooth (ADULT) syndrome is a rare form of autosomal 
      dominant ectodermal dysplasia due to mutations in the TP63 gene, a locus that has 
      also been implicated in other syndromic forms of ectodermal dysplasia. It shares 
      many phenotypic characteristics with other TP63 gene mutation syndromes, often 
      making an accurate diagnosis difficult. Long-term management and follow-up of the 
      various sequelae of ectodermal dysplasia require an accurate diagnosis. We report 
      a familial case of ADULT syndrome in a daughter, mother, and son and provide a 
      brief review of the clinical characteristics of this syndrome.
CI  - (c) 2016 Wiley Periodicals, Inc.
FAU - Whittington, Adam
AU  - Whittington A
AD  - Division of Dermatology, Ann and Robert H. Lurie Children's Hospital of Chicago, 
      Northwestern University, Chicago, Illinois.
FAU - Stein, Sarah
AU  - Stein S
AD  - Section of Dermatology, University of Chicago, Chicago, Illinois.
FAU - Kenner-Bell, Brandi
AU  - Kenner-Bell B
AD  - Division of Dermatology, Ann and Robert H. Lurie Children's Hospital of Chicago, 
      Northwestern University, Chicago, Illinois. bmkbell@gmail.com.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
DEP - 20160728
PL  - United States
TA  - Pediatr Dermatol
JT  - Pediatric dermatology
JID - 8406799
RN  - 0 (TP63 protein, human)
RN  - 0 (Transcription Factors)
RN  - 0 (Tumor Suppressor Proteins)
RN  - Propping Zerres syndrome
SB  - IM
MH  - Abnormalities, Multiple/diagnosis/epidemiology
MH  - Adolescent
MH  - Adult
MH  - Anodontia/*diagnosis/epidemiology/genetics
MH  - Breast/*abnormalities
MH  - Child
MH  - Diagnosis, Differential
MH  - Ectodermal Dysplasia/*diagnosis/epidemiology/genetics
MH  - Female
MH  - *Genetic Predisposition to Disease
MH  - Humans
MH  - Lacrimal Duct Obstruction/*diagnosis/epidemiology/genetics
MH  - Limb Deformities, Congenital/*diagnosis/epidemiology/genetics
MH  - Mothers
MH  - Mutation
MH  - Nails, Malformed/*diagnosis/epidemiology/genetics
MH  - *Pedigree
MH  - Pigmentation Disorders/*diagnosis/epidemiology/genetics
MH  - Prognosis
MH  - Risk Assessment
MH  - Severity of Illness Index
MH  - Siblings
MH  - Transcription Factors/*genetics
MH  - Tumor Suppressor Proteins/*genetics
EDAT- 2016/07/30 06:00
MHDA- 2017/04/01 06:00
CRDT- 2016/07/30 06:00
PHST- 2016/07/30 06:00 [entrez]
PHST- 2016/07/30 06:00 [pubmed]
PHST- 2017/04/01 06:00 [medline]
AID - 10.1111/pde.12938 [doi]
PST - ppublish
SO  - Pediatr Dermatol. 2016 Sep;33(5):e322-6. doi: 10.1111/pde.12938. Epub 2016 Jul 
      28.