PMID- 27470983
OWN - NLM
STAT- MEDLINE
DCOM- 20170615
LR  - 20170615
IS  - 1522-726X (Electronic)
IS  - 1522-1946 (Linking)
VI  - 89
IP  - 4
DP  - 2017 Mar 1
TI  - Evaluating the quality of implantation of percutaneous ventricular restoration 
      device (Parachute(R)) by cardiac computed tomography.
PG  - E104-E111
LID - 10.1002/ccd.26644 [doi]
AB  - BACKGROUND: The Parachute is a novel percutaneously implanted ventricular 
      partitioning device (VPD) that has emerged as a safe and feasible treatment 
      option for patients with heart failure following anterior wall myocardial 
      infarction. VPD efficacy is likely dependent on optimal device placement, but to 
      date there are no published data examining the effect of device positioning on 
      patient outcomes. METHODS AND RESULTS: We retrospectively identified 32 patients 
      successfully implanted with the Parachute device, all of whom underwent cardiac 
      computed tomography (CCT) at baseline and after 6 months of follow-up. Patients 
      were divided into two groups based on self-reported improvement in New York Heart 
      Association (NYHA) functional class: "not improved NYHA" (n = 12) and "improved 
      NYHA" (n = 20). There were significant differences between both groups with 
      regard to device positioning on follow-up CCT. Compared to patients with 
      "improved NYHA," patients with "not improved NYHA" had longer distances from 
      device foot to left ventricular apex (8.0 +/- 4.9 vs. 2.9 +/- 4.6 mm; P = 0.01), and 
      higher lateral angles (18.0 +/- 14 vs. 9.1 +/- 6.8 degrees; P = 0.02), respectively. 
      There was no significant difference between the two groups in landing zone 
      (45.4 +/- 7. vs. 45.1 +/- 6.9 mm; P = 0.92) and inferior angle (14.0 +/- 11.9 vs. 
      14.3 +/- 10.1 degrees; P = 0.95). There was a numerically larger malapposition area 
      in the "not improved NYHA" group (5.1 +/- 4.5 vs. 3.2 +/- 2.2 cm2; P = 0.12). 
      CONCLUSION: Quality of Parachute implant impacted clinical outcome, these 
      findings should be applied prospectively in helping operators to achieve optimal 
      implant. (c) 2016 Wiley Periodicals, Inc.
CI  - (c) 2016 Wiley Periodicals, Inc.
FAU - Alaiti, Mohamad Amer
AU  - Alaiti MA
AD  - Department of Medicine, Harrington Heart and Vascular Institute, University 
      Hospitals, Case Medical Center, Cleveland, Ohio.
FAU - Fares, Anas
AU  - Fares A
AD  - Department of Medicine, Harrington Heart and Vascular Institute, University 
      Hospitals, Case Medical Center, Cleveland, Ohio.
FAU - Erglis, Andrejs
AU  - Erglis A
AD  - Department of Medicine, Institute of Cardiology, University of Latvia, Pauls 
      Stradins Clinical University Hospital, Riga, Latvia.
FAU - Nshisso, Lemba
AU  - Nshisso L
AD  - Department of Medicine, Harrington Heart and Vascular Institute, University 
      Hospitals, Case Medical Center, Cleveland, Ohio.
FAU - Shaikh, Kashif
AU  - Shaikh K
AD  - Department of Medicine, Harrington Heart and Vascular Institute, University 
      Hospitals, Case Medical Center, Cleveland, Ohio.
FAU - DeCicco, Anthony E
AU  - DeCicco AE
AD  - Department of Medicine, Harrington Heart and Vascular Institute, University 
      Hospitals, Case Medical Center, Cleveland, Ohio.
FAU - Nasif, Marwan
AU  - Nasif M
AD  - Department of Medicine, Harrington Heart and Vascular Institute, University 
      Hospitals, Case Medical Center, Cleveland, Ohio.
FAU - Alkhalil, Ahmad
AU  - Alkhalil A
AD  - Department of Medicine, Harrington Heart and Vascular Institute, University 
      Hospitals, Case Medical Center, Cleveland, Ohio.
FAU - Ince, Huseyin
AU  - Ince H
AD  - Department of Cardiology, Vivantes Klinikum Im Friedrichshain Und Am Urban, 
      Berlin, Germany and Rostock University Medical Center, Rostock, Germany.
FAU - Abraham, William T
AU  - Abraham WT
AD  - Division of Cardiovascular Medicine, the Ohio State University, Columbus, Ohio.
FAU - Simon, Daniel I
AU  - Simon DI
AD  - Department of Medicine, Harrington Heart and Vascular Institute, University 
      Hospitals, Case Medical Center, Cleveland, Ohio.
FAU - Costa, Marco A
AU  - Costa MA
AD  - Department of Medicine, Harrington Heart and Vascular Institute, University 
      Hospitals, Case Medical Center, Cleveland, Ohio.
FAU - Attizzani, Guilherme F
AU  - Attizzani GF
AD  - Department of Medicine, Harrington Heart and Vascular Institute, University 
      Hospitals, Case Medical Center, Cleveland, Ohio.
FAU - Bezerra, Hiram G
AU  - Bezerra HG
AD  - Department of Medicine, Harrington Heart and Vascular Institute, University 
      Hospitals, Case Medical Center, Cleveland, Ohio.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20160729
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the 
      Society for Cardiac Angiography & Interventions
JID - 100884139
SB  - IM
MH  - Cardiac Catheterization/*methods
MH  - Cardiac Surgical Procedures/*methods
MH  - Equipment Design
MH  - Feasibility Studies
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Failure/diagnosis/physiopathology/*surgery
MH  - Heart Ventricles/diagnostic imaging/physiopathology/*surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Stroke Volume
MH  - Surgery, Computer-Assisted/*methods
MH  - Time Factors
MH  - Tomography, X-Ray Computed/*methods
MH  - Treatment Outcome
MH  - Ventricular Remodeling/*physiology
OTO - NOTNLM
OT  - electron beam CT/multidetector CT
OT  - heart failure
OT  - imaging
OT  - interventional devices/innovation
EDAT- 2016/07/30 06:00
MHDA- 2017/06/16 06:00
CRDT- 2016/07/30 06:00
PHST- 2016/02/12 00:00 [received]
PHST- 2016/06/05 00:00 [accepted]
PHST- 2016/07/30 06:00 [pubmed]
PHST- 2017/06/16 06:00 [medline]
PHST- 2016/07/30 06:00 [entrez]
AID - 10.1002/ccd.26644 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2017 Mar 1;89(4):E104-E111. doi: 10.1002/ccd.26644. 
      Epub 2016 Jul 29.