PMID- 27477413 OWN - NLM STAT- MEDLINE DCOM- 20170322 LR - 20181202 IS - 1349-7235 (Electronic) IS - 0918-2918 (Linking) VI - 55 IP - 15 DP - 2016 TI - Sarcoid Myositis with Anti-Ku Antibody Consistent with both Sarcoidosis and Polymyositis. PG - 2049-53 LID - 10.2169/internalmedicine.55.5816 [doi] AB - We herein describe a case of sarcoid myositis with anti-Ku antibody positivity. Pathological findings of the muscle were compatible with sarcoidosis, but could not be completely distinguished from myositis diseases that arise from other causes. According to a physical examination, pathological findings, the detection of anti-Ku antibody and the human leukocyte antigen (HLA)-DPB1 allele, we strongly suspected that the patient developed both sarcoidosis and polymyositis. Sarcoidosis is often complicated by autoimmune diseases. This case suggests the possibility that sarcoidosis and other autoimmune diseases may have common causal genetic factors. FAU - Awano, Nobuyasu AU - Awano N AD - Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan. FAU - Fukuda, Kensuke AU - Fukuda K FAU - Sakayori, Masashi AU - Sakayori M FAU - Kondoh, Keisuke AU - Kondoh K FAU - Ono, Ryu AU - Ono R FAU - Moriya, Atsuko AU - Moriya A FAU - Ando, Tsunehiro AU - Ando T FAU - Kumasaka, Toshio AU - Kumasaka T FAU - Takemura, Tamiko AU - Takemura T FAU - Ikushima, Soichiro AU - Ikushima S LA - eng PT - Case Reports PT - Journal Article DEP - 20160801 PL - Japan TA - Intern Med JT - Internal medicine (Tokyo, Japan) JID - 9204241 RN - 0 (Antibodies, Antinuclear) RN - EC 4.2.99.- (Ku Autoantigen) SB - IM MH - Antibodies, Antinuclear/*blood MH - Humans MH - Ku Autoantigen/*blood MH - Muscle Weakness/etiology MH - Myositis/blood/complications/*diagnosis MH - Polymyositis/blood/complications/*diagnosis MH - Sarcoidosis/blood/complications/*diagnosis EDAT- 2016/08/02 06:00 MHDA- 2017/03/23 06:00 CRDT- 2016/08/02 06:00 PHST- 2016/08/02 06:00 [entrez] PHST- 2016/08/02 06:00 [pubmed] PHST- 2017/03/23 06:00 [medline] AID - 10.2169/internalmedicine.55.5816 [doi] PST - ppublish SO - Intern Med. 2016;55(15):2049-53. doi: 10.2169/internalmedicine.55.5816. Epub 2016 Aug 1.