PMID- 27477634
OWN - NLM
STAT- MEDLINE
DCOM- 20170417
LR  - 20181202
IS  - 2050-7895 (Electronic)
IS  - 2050-7887 (Linking)
VI  - 18
IP  - 9
DP  - 2016 Sep 14
TI  - The origin and evolution of assessment criteria for persistent, bioaccumulative 
      and toxic (PBT) chemicals and persistent organic pollutants (POPs).
PG  - 1114-28
LID - 10.1039/c6em00311g [doi]
AB  - General public concern over the effects of persistent chemicals began in the 
      early 1960s. Since then, significant scientific advances have increased our 
      understanding of persistent, bioaccumulative, and toxic (PBT) chemicals and the 
      properties and processes that influence their fates in, and adverse effects on, 
      human health and the environment. In addition to the scientific advances, a 
      number of legislations and agreements for national, international, and global 
      identification and control of PBT chemicals have been adopted. However, some of 
      the rationales and thoughts that were relied upon when the first criteria were 
      developed to identify and categorize PBT chemicals and then POPs (persistent 
      organic pollutants) have not been carried forward. Criteria have been based upon 
      available data of neutral hydrophobic substances as reference chemicals, derived 
      under laboratory conditions. They evolved over the last decades due to the 
      diversification of the protection aims under various national regulatory 
      frameworks and international agreements, advances in methods for estimation of 
      physical/chemical properties, and the identification of chemicals which are 
      non-traditional POPs. Criteria are not defined purely by science; they also are 
      subject to the aims of policy. This paper offers a historical perspective on the 
      development of criteria for PBT chemicals and POPs. It also offers suggestions 
      for rationalization of protection goals, describes some emerging procedures for 
      identification of compounds of concern, and proposes information that needs to be 
      considered when applying criteria to screening and/or evaluation of new 
      chemicals.
FAU - Matthies, Michael
AU  - Matthies M
AD  - Institute of Environmental Systems Research, University of Osnabruck, Osnabruck 
      D-49069, Germany. matthies@uos.de.
FAU - Solomon, Keith
AU  - Solomon K
FAU - Vighi, Marco
AU  - Vighi M
FAU - Gilman, Andy
AU  - Gilman A
FAU - Tarazona, Jose V
AU  - Tarazona JV
LA  - eng
PT  - Historical Article
PT  - Journal Article
DEP - 20160801
PL  - England
TA  - Environ Sci Process Impacts
JT  - Environmental science. Processes & impacts
JID - 101601576
RN  - 0 (Environmental Pollutants)
RN  - 0 (Organic Chemicals)
SB  - IM
MH  - Environmental Monitoring/*history/legislation & jurisprudence/methods
MH  - Environmental Pollutants/*analysis/chemistry
MH  - Environmental Pollution/analysis/legislation & jurisprudence
MH  - History, 20th Century
MH  - History, 21st Century
MH  - Humans
MH  - Organic Chemicals/*analysis/chemistry
EDAT- 2016/08/02 06:00
MHDA- 2017/04/18 06:00
CRDT- 2016/08/02 06:00
PHST- 2016/08/02 06:00 [entrez]
PHST- 2016/08/02 06:00 [pubmed]
PHST- 2017/04/18 06:00 [medline]
AID - 10.1039/c6em00311g [doi]
PST - ppublish
SO  - Environ Sci Process Impacts. 2016 Sep 14;18(9):1114-28. doi: 10.1039/c6em00311g. 
      Epub 2016 Aug 1.