PMID- 27484765
OWN - NLM
STAT- MEDLINE
DCOM- 20180831
LR  - 20181202
IS  - 1993-0402 (Electronic)
IS  - 1672-0415 (Linking)
VI  - 23
IP  - 7
DP  - 2017 Jul
TI  - Is manipulative therapy clinically necessary for relief of neck pain? A 
      systematic review and meta-analysis.
PG  - 543-554
LID - 10.1007/s11655-016-2506-1 [doi]
AB  - OBJECTIVE: To summarize and critically assess the effificacy of Eastern and 
      Western manipulative therapies for the treatment of neck pain in adults. METHODS: 
      A search of PubMed/MEDLINE, the Cochrane Central Register of Controlled Trials, 
      ClinicalTrials.gov, EMBASE, etc. from their inception date to January 2014 with 
      Chinese, Japanese, and Korean databases. Two reviewers independently selected 
      randomized controlled trials (RCTs) with negative control or blank control, 
      extracted data and assessed methodological quality. Meta-analysis and levels of 
      evidence were performed by Revman5.1 and Grades of Recommendations Assessment, 
      Development and Evaluation (GRADE) approach. RESULTS: Nineteen clinical trials 
      with adequate randomization were included in this review, 11 of them had a low 
      risk of bias. The primary outcome for short-term pain had no significant 
      differences, however, the secondary outcome, only the Numerical Pain Rating Scale 
      (NPRS) score of intermediate-term [n=916, pooled mean differences (MD) =-0.29, 
      P=0.02], the Neck Disability Index (NDI) score of short-term (n=1,145, pooled 
      MD=-2.10, P<0.01), and intermediate-term (n=987, pooled MD=-1.45, P=0.01) were 
      signifificantly reduced with moderate quality evidence. However, it supported the 
      minimally clinically important difference (MCID) of the Visual Analogue Scale and 
      NPRS pain score to be 13 mm, while NDI was 3.5 points. The meta-analysis only 
      suggested a trend in favor of manipulative therapy rather than clinical 
      signifificance. CONCLUSIONS: The results do not support the existing evidences 
      for the clinical value of Eastern or Western manipulative therapy for neck pain 
      of short-term follow-up according to MCIDs. The limitations of our review related 
      to blinding, allocation concealment and small sample size.
FAU - Yao, Min
AU  - Yao M
AD  - Institute of Spine Disease, Longhua Hospital, Shanghai University of Traditional 
      Chinese Medicine, Shanghai, 200032, China.
FAU - Sun, Yue-Li
AU  - Sun YL
AD  - Institute of Spine Disease, Longhua Hospital, Shanghai University of Traditional 
      Chinese Medicine, Shanghai, 200032, China.
FAU - Dun, Rong-Liang
AU  - Dun RL
AD  - Yueyang College of Clinical Medicine, Shanghai University of Traditional Chinese 
      Medicine, Shanghai, 200403, China.
FAU - Lan, Tian-Ying
AU  - Lan TY
AD  - Shuguang College of Clinical Medicine, Shanghai University of Traditional Chinese 
      Medicine, Shanghai, 200025, China.
FAU - Li, Jin-Long
AU  - Li JL
AD  - Institute of Spine Disease, Longhua Hospital, Shanghai University of Traditional 
      Chinese Medicine, Shanghai, 200032, China.
FAU - Lee, Hyo Jin
AU  - Lee HJ
AD  - Longhua College of Clinical Medicine, Shanghai University of Traditional Chinese 
      Medicine, Shanghai, 200032, China.
FAU - Haraguchi, Noriko
AU  - Haraguchi N
AD  - Shuguang College of Clinical Medicine, Shanghai University of Traditional Chinese 
      Medicine, Shanghai, 200025, China.
FAU - Wang, Yong-Jun
AU  - Wang YJ
AD  - Institute of Spine Disease, Longhua Hospital, Shanghai University of Traditional 
      Chinese Medicine, Shanghai, 200032, China.
FAU - Cui, Xue-Jun
AU  - Cui XJ
AD  - Institute of Spine Disease, Longhua Hospital, Shanghai University of Traditional 
      Chinese Medicine, Shanghai, 200032, China. 13917715524@139.com.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20160802
PL  - China
TA  - Chin J Integr Med
JT  - Chinese journal of integrative medicine
JID - 101181180
SB  - IM
MH  - Costs and Cost Analysis
MH  - Disability Evaluation
MH  - Humans
MH  - *Musculoskeletal Manipulations/adverse effects/economics
MH  - Neck Pain/economics/*therapy
MH  - Publication Bias
MH  - Treatment Outcome
OTO - NOTNLM
OT  - manipulative therapy
OT  - meta-analysis
OT  - minimally clinically important difference
OT  - neck pain
OT  - systematic review
EDAT- 2016/08/04 06:00
MHDA- 2018/09/01 06:00
CRDT- 2016/08/04 06:00
PHST- 2014/05/16 00:00 [received]
PHST- 2016/08/04 06:00 [pubmed]
PHST- 2018/09/01 06:00 [medline]
PHST- 2016/08/04 06:00 [entrez]
AID - 10.1007/s11655-016-2506-1 [pii]
AID - 10.1007/s11655-016-2506-1 [doi]
PST - ppublish
SO  - Chin J Integr Med. 2017 Jul;23(7):543-554. doi: 10.1007/s11655-016-2506-1. Epub 
      2016 Aug 2.