PMID- 27490315 OWN - NLM STAT- MEDLINE DCOM- 20171220 LR - 20181202 IS - 1879-0771 (Electronic) IS - 0895-6111 (Linking) VI - 53 DP - 2016 Oct TI - Penalized weighted least-squares approach for multienergy computed tomography image reconstruction via structure tensor total variation regularization. PG - 19-29 LID - S0895-6111(16)30067-2 [pii] LID - 10.1016/j.compmedimag.2016.07.002 [doi] AB - Multienergy computed tomography (MECT) allows identifying and differentiating different materials through simultaneous capture of multiple sets of energy-selective data belonging to specific energy windows. However, because sufficient photon counts are not available in each energy window compared with that in the whole energy window, the MECT images reconstructed by the analytical approach often suffer from poor signal-to-noise and strong streak artifacts. To address the particular challenge, this work presents a penalized weighted least-squares (PWLS) scheme by incorporating the new concept of structure tensor total variation (STV) regularization, which is henceforth referred to as 'PWLS-STV' for simplicity. Specifically, the STV regularization is derived by penalizing higher-order derivatives of the desired MECT images. Thus it could provide more robust measures of image variation, which can eliminate the patchy artifacts often observed in total variation (TV) regularization. Subsequently, an alternating optimization algorithm was adopted to minimize the objective function. Extensive experiments with a digital XCAT phantom and meat specimen clearly demonstrate that the present PWLS-STV algorithm can achieve more gains than the existing TV-based algorithms and the conventional filtered backpeojection (FBP) algorithm in terms of both quantitative and visual quality evaluations. CI - Copyright (c) 2016 Elsevier Ltd. All rights reserved. FAU - Zeng, Dong AU - Zeng D AD - Department of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515, China; Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, China. FAU - Gao, Yuanyuan AU - Gao Y AD - Department of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515, China; Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, China. FAU - Huang, Jing AU - Huang J AD - Department of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515, China; Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, China. FAU - Bian, Zhaoying AU - Bian Z AD - Department of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515, China; Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, China. FAU - Zhang, Hua AU - Zhang H AD - Department of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515, China; Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, China. FAU - Lu, Lijun AU - Lu L AD - Department of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515, China; Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, China. FAU - Ma, Jianhua AU - Ma J AD - Department of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515, China; Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, Guangdong 510515, China. Electronic address: jhma@smu.edu.cn. LA - eng PT - Journal Article DEP - 20160719 PL - United States TA - Comput Med Imaging Graph JT - Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society JID - 8806104 SB - IM MH - Algorithms MH - *Image Processing, Computer-Assisted MH - Least-Squares Analysis MH - *Tomography, X-Ray Computed OTO - NOTNLM OT - Multienergy computed tomography OT - Penalized weighted least-squares OT - Regularization OT - Structure tensor total variation EDAT- 2016/08/05 06:00 MHDA- 2017/12/21 06:00 CRDT- 2016/08/05 06:00 PHST- 2015/12/11 00:00 [received] PHST- 2016/06/13 00:00 [revised] PHST- 2016/07/14 00:00 [accepted] PHST- 2016/08/05 06:00 [entrez] PHST- 2016/08/05 06:00 [pubmed] PHST- 2017/12/21 06:00 [medline] AID - S0895-6111(16)30067-2 [pii] AID - 10.1016/j.compmedimag.2016.07.002 [doi] PST - ppublish SO - Comput Med Imaging Graph. 2016 Oct;53:19-29. doi: 10.1016/j.compmedimag.2016.07.002. Epub 2016 Jul 19.