PMID- 27496216
OWN - NLM
STAT- MEDLINE
DCOM- 20180126
LR  - 20191210
IS  - 1523-6536 (Electronic)
IS  - 1083-8791 (Linking)
VI  - 22
IP  - 11
DP  - 2016 Nov
TI  - HapLogic: A Predictive Human Leukocyte Antigen-Matching Algorithm to Enhance 
      Rapid Identification of the Optimal Unrelated Hematopoietic Stem Cell Sources for 
      Transplantation.
PG  - 2038-2046
LID - S1083-8791(16)30258-0 [pii]
LID - 10.1016/j.bbmt.2016.07.022 [doi]
AB  - The search for a suitable human leukocyte antigen (HLA)-matched unrelated adult 
      stem cell donor (URD) or umbilical cord blood unit (UCB) is a complex process. 
      The National Marrow Donor Program (NMDP) developed a search algorithm known as 
      HapLogic, which is currently provided within the NMDP Traxis application. The 
      HapLogic algorithm has been in use since 2006 and has advanced URD/UCB 
      HLA-matching technology. The algorithm has been shown to have high predictive 
      accuracy, which can streamline URD/UCB selection and drive efficiencies in the 
      search process to the benefit of the stem cell transplantation community. Here, 
      we describe the fundamental components of the NMDP matching algorithm, output, 
      validation, and future directions.
CI  - Copyright (c) 2016 The American Society for Blood and Marrow Transplantation. 
      Published by Elsevier Inc. All rights reserved.
FAU - Dehn, Jason
AU  - Dehn J
AD  - National Marrow Donor Program, Minneapolis, Minnesota. Electronic address: 
      jdehn@nmdp.org.
FAU - Setterholm, Michelle
AU  - Setterholm M
AD  - National Marrow Donor Program, Minneapolis, Minnesota.
FAU - Buck, Kelly
AU  - Buck K
AD  - National Marrow Donor Program, Minneapolis, Minnesota.
FAU - Kempenich, Jane
AU  - Kempenich J
AD  - National Marrow Donor Program, Minneapolis, Minnesota.
FAU - Beduhn, Beth
AU  - Beduhn B
AD  - National Marrow Donor Program, Minneapolis, Minnesota.
FAU - Gragert, Loren
AU  - Gragert L
AD  - National Marrow Donor Program, Minneapolis, Minnesota; Department of Pathology 
      and Laboratory Medicine, Tulane Cancer Center, Tulane University School of 
      Medicine, New Orleans, Louisiana.
FAU - Madbouly, Abeer
AU  - Madbouly A
AD  - National Marrow Donor Program, Minneapolis, Minnesota.
FAU - Fingerson, Stephanie
AU  - Fingerson S
AD  - National Marrow Donor Program, Minneapolis, Minnesota.
FAU - Maiers, Martin
AU  - Maiers M
AD  - National Marrow Donor Program, Minneapolis, Minnesota.
LA  - eng
PT  - Journal Article
PT  - Validation Study
DEP - 20160802
PL  - United States
TA  - Biol Blood Marrow Transplant
JT  - Biology of blood and marrow transplantation : journal of the American Society for 
      Blood and Marrow Transplantation
JID - 9600628
RN  - 0 (HLA Antigens)
SB  - IM
MH  - *Algorithms
MH  - HLA Antigens/immunology
MH  - Hematopoietic Stem Cell Transplantation/*methods
MH  - Hematopoietic Stem Cells/immunology
MH  - Histocompatibility Testing/*methods
MH  - Humans
MH  - Unrelated Donors
OTO - NOTNLM
OT  - Cord blood unit selection
OT  - Donor selection
OT  - HLA matching
OT  - Predictive algorithm
EDAT- 2016/08/09 06:00
MHDA- 2018/01/27 06:00
CRDT- 2016/08/07 06:00
PHST- 2016/05/10 00:00 [received]
PHST- 2016/07/29 00:00 [accepted]
PHST- 2016/08/09 06:00 [pubmed]
PHST- 2018/01/27 06:00 [medline]
PHST- 2016/08/07 06:00 [entrez]
AID - S1083-8791(16)30258-0 [pii]
AID - 10.1016/j.bbmt.2016.07.022 [doi]
PST - ppublish
SO  - Biol Blood Marrow Transplant. 2016 Nov;22(11):2038-2046. doi: 
      10.1016/j.bbmt.2016.07.022. Epub 2016 Aug 2.