PMID- 27500208
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160808
LR  - 20201001
IS  - 2373-8731 (Print)
IS  - 2373-8731 (Electronic)
IS  - 2373-8731 (Linking)
VI  - 1
IP  - 1
DP  - 2015 Feb
TI  - Postrenal Transplant Human T-Cell Lymphotropic Virus Type I-Associated 
      Myelopathy/Tropical Spastic Paraparesis: A Case Report and Review of the 
      Literature.
PG  - e3
LID - 10.1097/TXD.0000000000000512 [doi]
LID - e3
AB  - We report a case of human T-cell lymphotropic virus type I (HTLV-I)-associated 
      myelopathy/tropical spastic paraparesis (HAM/TSP), in a 59 year-old, 
      living-donor, renal transplant recipient from Jamaica. The patient's renal 
      transplant had been performed 11 years ago, and her organ donor was also from 
      Jamaica. Pretransplant HTLV-I serologic status for both the donor and recipient 
      was unknown. The prevalence of HTLV-I seropositivity in the United States and 
      Europe is low, and HAM/TSP is a rare occurrence. The positive predictive value of 
      HTLV-I screening in these regions is therefore, low. This has generated debate 
      among transplant societies regarding universal screening for HTLV-I before solid 
      organ transplantation. Very limited evidence is available for the prevention and 
      treatment of this devastating condition. Our case highlights the importance of 
      selected pretransplant screening for HTLV-I infection among organ donors and 
      candidates from endemic areas. We feel such testing may aid in the early 
      recognition of HAM/TSP and more timely initiation of treatment.
FAU - Torres, Julian Andres
AU  - Torres JA
AD  - Division of Infectious Diseases and Immunology at New York University Langone 
      Medical Center, Department of Medicine, New York University School of Medicine, 
      New York, NY.
FAU - Taimur, Sarah
AU  - Taimur S
AD  - Division of Infectious Diseases and Immunology at New York University Langone 
      Medical Center, Department of Medicine, New York University School of Medicine, 
      New York, NY.
LA  - eng
PT  - Case Reports
DEP - 20150305
PL  - United States
TA  - Transplant Direct
JT  - Transplantation direct
JID - 101651609
PMC - PMC4946443
COIS- The authors declare no funding or conflicts of interest.
EDAT- 2015/02/01 00:00
MHDA- 2015/02/01 00:01
PMCR- 2015/03/05
CRDT- 2016/08/09 06:00
PHST- 2014/11/30 00:00 [received]
PHST- 2015/01/06 00:00 [accepted]
PHST- 2016/08/09 06:00 [entrez]
PHST- 2015/02/01 00:00 [pubmed]
PHST- 2015/02/01 00:01 [medline]
PHST- 2015/03/05 00:00 [pmc-release]
AID - TXD14003 [pii]
AID - 10.1097/TXD.0000000000000512 [doi]
PST - epublish
SO  - Transplant Direct. 2015 Mar 5;1(1):e3. doi: 10.1097/TXD.0000000000000512. 
      eCollection 2015 Feb.