PMID- 27500758
OWN - NLM
STAT- MEDLINE
DCOM- 20171003
LR  - 20220318
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 222
DP  - 2016 Nov 1
TI  - Acupuncture for heart failure: A systematic review of clinical studies.
PG  - 321-331
LID - S0167-5273(16)31589-3 [pii]
LID - 10.1016/j.ijcard.2016.07.195 [doi]
AB  - BACKGROUND: Acupuncture has been used for treating heart failure mainly in 
      combination with conventional treatments, but evidence for its effectiveness and 
      safety has not been well established. Our aim was to review randomized controlled 
      trials (RCTs) on acupuncture for heart failure and assess the clinical evidence. 
      METHODS: Electronic databases such as Medline, EMBASE, Cochrane Central Register 
      of Controlled Trials (CENTRAL) and certain Chinese & Korean databases were 
      searched until October 2015. The main outcomes assessed were mortality, New York 
      Heart Association (NYHA) function classifications, and acupuncture-related 
      adverse events. The details of acupuncture intervention were also investigated. 
      RESULTS: Among 4107 publications, seven RCTs were included; most of them showed 
      considerable methodological flaws. We could not conduct a meta-analysis because 
      of the heterogeneity of the included studies. In one acute heart failure study, 
      acupuncture shortened intensive care unit (ICU) stay by 2.2days (95% CI 1.26, 
      3.14) and reduced the risk ratio of re-admission to 0.53 (95% CI 0.28, 0.99). 
      However, mortality was not affected. Hemodynamic parameters also showed 
      improvement. Another study reported an improved left ventricular ejection 
      fraction by 9.95% (95% CI 3.24, 16.66). In five chronic heart failure studies, 
      acupuncture improved exercise capacity, quality of life, hemodynamic parameters, 
      and time domain heart rate variability parameters. Acupuncture decreased NT-pro 
      BNP levels by 292.20 (95% CI -567.36, -17.04). No adverse effects were reported. 
      CONCLUSIONS: The effectiveness of acupuncture as a therapy for heart failure is 
      currently inconclusive. Further large and rigorous clinical trials are needed to 
      establish its clinical utility.
CI  - Copyright (c) 2016 Elsevier Ireland Ltd. All rights reserved.
FAU - Lee, Hojung
AU  - Lee H
AD  - Department of Clinical Korean Medicine, Graduate School, Kyung Hee University,23 
      Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea; Korean Medicine 
      Clinical Trial Center, Kyung Hee University Korean Medicine Hospital,23 
      Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic 
      address: innocent0515@naver.com.
FAU - Kim, Tae-Hun
AU  - Kim TH
AD  - Department of Clinical Korean Medicine, Graduate School, Kyung Hee University,23 
      Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea; Korean Medicine 
      Clinical Trial Center, Kyung Hee University Korean Medicine Hospital,23 
      Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic 
      address: rockandmineral@gmail.com.
FAU - Leem, Jungtae
AU  - Leem J
AD  - Department of Clinical Korean Medicine, Graduate School, Kyung Hee University,23 
      Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea; Korean Medicine 
      Clinical Trial Center, Kyung Hee University Korean Medicine Hospital,23 
      Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic 
      address: julcho@naver.com.
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20160730
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
MH  - Acupuncture Therapy/*methods
MH  - Clinical Trials as Topic/*methods
MH  - Databases, Factual
MH  - Heart Failure/diagnosis/*epidemiology/*therapy
MH  - Humans
OTO - NOTNLM
OT  - Acupuncture
OT  - Acupuncture therapy
OT  - Electroacupuncture
OT  - Heart failure
OT  - Systematic review
EDAT- 2016/08/09 06:00
MHDA- 2017/10/04 06:00
CRDT- 2016/08/09 06:00
PHST- 2016/05/29 00:00 [received]
PHST- 2016/07/28 00:00 [accepted]
PHST- 2016/08/09 06:00 [entrez]
PHST- 2016/08/09 06:00 [pubmed]
PHST- 2017/10/04 06:00 [medline]
AID - S0167-5273(16)31589-3 [pii]
AID - 10.1016/j.ijcard.2016.07.195 [doi]
PST - ppublish
SO  - Int J Cardiol. 2016 Nov 1;222:321-331. doi: 10.1016/j.ijcard.2016.07.195. Epub 
      2016 Jul 30.