PMID- 27504709
OWN - NLM
STAT- MEDLINE
DCOM- 20170220
LR  - 20190221
IS  - 1546-3141 (Electronic)
IS  - 0361-803X (Linking)
VI  - 207
IP  - 5
DP  - 2016 Nov
TI  - Association of Xerostomia and Ultrasonographic Features of the Major Salivary 
      Glands After Radioactive Iodine Ablation for Papillary Thyroid Carcinoma.
PG  - 1077-1081
AB  - OBJECTIVE: The objective of this study is to evaluate the association between 
      xerostomia and sonographic features of the major salivary glands after patients 
      undergo radioactive iodine ablation (RIA) for papillary thyroid carcinoma (PTC). 
      MATERIALS AND METHODS: The study included 256 consecutive patients who underwent 
      total thyroidectomy, RIA, and neck ultrasound examinations. Changes in the 
      ultrasound features of the parotid and submandibular glands after RIA were 
      evaluated retrospectively by a single radiologist, on the basis of direct 
      comparison of sonograms obtained before and after RIA. Clinical data, including 
      the presence of xerostomia, were investigated retrospectively by the same 
      radiologist via a review of the electronic medical records. RESULTS: For 111 of 
      the 256 patients (43.4%), ultrasound examination revealed changes in the major 
      salivary glands after RIA. The presence of xerostomia was undetermined in 85 of 
      the 256 patients. Among the remaining 171 patients, the frequency of xerostomia 
      was 36.8% (63/171). When patients with xerostomia were compared with those 
      without xerostomia, no statistically significant differences in patient sex and 
      age, the dose of RIA received, or the number of RIA sessions were noted (p > 
      0.05). Considering the changes in the ultrasound features of the major salivary 
      glands after RIA, no statistically significant association was found between 
      xerostomia and the number of involved major salivary glands or the presence of an 
      involved submandibular gland (p > 0.05). CONCLUSION: In this study, ultrasound 
      was unhelpful for evaluating xerostomia after RIA in patients with PTC.
FAU - Soo Roh, Sang
AU  - Soo Roh S
AD  - 1 Department of Radiology, Busan Paik Hospital, Inje University College of 
      Medicine, 75, Bokji-ro, Busanjin-gu, Busan, South Korea 47392.
FAU - Wook Kim, Dong
AU  - Wook Kim D
AD  - 1 Department of Radiology, Busan Paik Hospital, Inje University College of 
      Medicine, 75, Bokji-ro, Busanjin-gu, Busan, South Korea 47392.
FAU - Jin Baek, Hye
AU  - Jin Baek H
AD  - 2 Department of Radiology, Gyeongsang National University Changwon Hospital, 
      Gyeongsang National University School of Medicine, Changwon, South Korea.
LA  - eng
PT  - Journal Article
DEP - 20160809
PL  - United States
TA  - AJR Am J Roentgenol
JT  - AJR. American journal of roentgenology
JID - 7708173
RN  - 0 (Iodine Radioisotopes)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Carcinoma/*radiotherapy
MH  - Carcinoma, Papillary
MH  - Female
MH  - Humans
MH  - Iodine Radioisotopes/therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Radiation Injuries/*diagnostic imaging/*etiology
MH  - Retrospective Studies
MH  - Salivary Glands/*radiation effects
MH  - Thyroid Cancer, Papillary
MH  - Thyroid Neoplasms/*radiotherapy
MH  - Ultrasonography/*methods
MH  - Xerostomia/*diagnostic imaging/*etiology
OTO - NOTNLM
OT  - major salivary glands
OT  - papillary thyroid carcinoma
OT  - radioactive iodine ablation
OT  - ultrasonography, xerostomia
EDAT- 2016/10/22 06:00
MHDA- 2017/08/18 06:00
CRDT- 2016/08/10 06:00
PHST- 2016/10/22 06:00 [pubmed]
PHST- 2017/08/18 06:00 [medline]
PHST- 2016/08/10 06:00 [entrez]
AID - 10.2214/AJR.15.15776 [doi]
PST - ppublish
SO  - AJR Am J Roentgenol. 2016 Nov;207(5):1077-1081. doi: 10.2214/AJR.15.15776. Epub 
      2016 Aug 9.