PMID- 27509000 OWN - NLM STAT- MEDLINE DCOM- 20171218 LR - 20171218 IS - 1439-1902 (Electronic) IS - 0171-6425 (Linking) VI - 65 IP - 8 DP - 2017 Dec TI - Individualized Surgical Treatments for Children with Ebstein Anomaly. PG - 649-655 LID - 10.1055/s-0036-1586203 [doi] AB - Objective Ebstein anomaly is a rare type of tricuspid malformation. The present surgical methods to resolve this anomaly include tricuspid valvuloplasty, palliative surgery, and tricuspid valve replacement. The purpose of this study was to evaluate the short- and midterm outcomes of different surgical treatments among children with Ebstein anomaly. Methods This was a retrospective study of 136 Ebstein anomaly patients undergoing surgery at our institution from January, 2006 to August, 2015. This cohort included 118 patients receiving tricuspid valvuloplasty, 14 patients receiving palliative surgery and 4 patients receiving tricuspid valve replacement. Results There were two in-hospital deaths and one delayed death 6 months after bidirectional cavopulmonary shunt during a second-stage operation; thus, the mortality rate was 2.2% (3/136). The follow-up variables included echocardiography, chest radiography, oxygen saturation, and cardiac function. After a mean follow-up duration of 35.8 +/- 16.5 months (range: 6-98 months), all survivors had no indications for reoperation; the oxygen saturation following radical surgery and palliative surgery was 95 to 100% and 85 to 95%, respectively. Most of the patients exhibited an improved New York Heart Association (NYHA) functional class from III or IV preoperatively to I or II at follow-up; only two patients who underwent the Fontan procedure continued to exhibit NYHA functional class III. In most patients, tricuspid regurgitation (TR) degree decreased from moderate or severe preoperatively to mild or moderate at follow-up and only six patients continued to exhibit severe TR at follow-up. Conclusions Individualization of surgical methods based on different indications, including age, associated malformations, tricuspid anatomy, cardiac function, and intraoperative status, could effectively improve the outcomes of Ebstein anomaly patients. CI - Georg Thieme Verlag KG Stuttgart . New York. FAU - Jinghao, Zheng AU - Jinghao Z AD - Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Heart Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China. FAU - Kai, Luo AU - Kai L AD - Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Heart Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China. FAU - Yanhui, Huang AU - Yanhui H AD - Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Heart Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China. FAU - Zhongqun, Zhu AU - Zhongqun Z AD - Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Heart Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China. FAU - Botao, Gao AU - Botao G AD - Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Heart Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China. FAU - Xinwei, Du AU - Xinwei D AD - Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Heart Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China. FAU - Zhiwei, Xu AU - Zhiwei X AD - Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Heart Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China. FAU - Jinfen, Liu AU - Jinfen L AD - Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Heart Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China. LA - eng PT - Journal Article DEP - 20160810 PL - Germany TA - Thorac Cardiovasc Surg JT - The Thoracic and cardiovascular surgeon JID - 7903387 SB - IM MH - Adolescent MH - Balloon Valvuloplasty MH - Child MH - Child, Preschool MH - China MH - Ebstein Anomaly/diagnostic imaging/mortality/physiopathology/*surgery MH - Female MH - Heart Valve Prosthesis MH - *Heart Valve Prosthesis Implantation/adverse effects/instrumentation/mortality MH - Hospital Mortality MH - Humans MH - Infant MH - Male MH - Palliative Care MH - Recovery of Function MH - Retrospective Studies MH - Severity of Illness Index MH - Time Factors MH - Tomography, X-Ray Computed MH - Treatment Outcome MH - Tricuspid Valve/abnormalities/diagnostic imaging/physiopathology/*surgery MH - Tricuspid Valve Insufficiency/diagnostic imaging/mortality/physiopathology/*surgery COIS- Conflict of Interest: None declared. EDAT- 2016/08/11 06:00 MHDA- 2017/12/19 06:00 CRDT- 2016/08/11 06:00 PHST- 2016/08/11 06:00 [pubmed] PHST- 2017/12/19 06:00 [medline] PHST- 2016/08/11 06:00 [entrez] AID - 10.1055/s-0036-1586203 [doi] PST - ppublish SO - Thorac Cardiovasc Surg. 2017 Dec;65(8):649-655. doi: 10.1055/s-0036-1586203. Epub 2016 Aug 10.