PMID- 27510261 OWN - NLM STAT- MEDLINE DCOM- 20170327 LR - 20170817 VI - 126 IP - 7-8 DP - 2016 Aug 11 TI - Heart failure in elderly patients: differences in clinical characteristics and predictors of 1-year outcome in the Polish ESC-HF Long-Term Registry. PG - 502-13 LID - 10.20452/pamw.3490 [doi] AB - INTRODUCTION Heart failure (HF) is the leading cause of hospitalization in elderly patients. OBJECTIVES The aim of the study was to examine the clinical profile and 1-year outcomes of elderly patients (aged >/=65 years) compared with younger patients (aged <65 years) hospitalized for HF decompensation, as well as clinical differences among elderly patients aged 65-74 years and those aged >/=75 years. PATIENTS AND METHODS The primary endpoint (PE; all-cause death) and the secondary endpoint (SE; all-cause death or rehospitalization for HF worsening) were assessed at 1 year in a group of 765 hospitalized Polish participants of the ESC-HF Long-Term Registry. RESULTS The PE was observed in 9.1% of patients aged <65 years; 18.5% of those aged >/=65 years (P = 0.0001); 14.5% of those aged 65-74 years; and 21.6% of those aged >/=75 years (P = 0.07). The SE occurred in 28.0% of patients aged <65 years; 36.1% of those aged >/=65 years (P = 0.04); 29.2% of those aged 65-74 years; and 41.2% of those aged >/=75 years (P = 0.01). Independent predictors of the PE in patients aged >/=65 years were as follows: chronic obstructive pulmonary disease (COPD), systolic blood pressure (SBP), New York Heart Association (NYHA) class, beta-blocker use; in patients aged 65-74 years: coronary revascularization, NYHA class, sodium, and creatinine; in patients aged >/=75 years: NYHA class and SBP. Independent predictors of the SE in patients aged >/=65 years were as follows: COPD, NYHA class, potassium, SBP, and physical activity; in patients aged <65 years: chronic kidney disease (CKD), NYHA, and SBP; in patients aged 65-74 years: NYHA and creatinine; and in patients aged >/=75 years, previous HF hospitalization, coronary artery disease, CKD, COPD, alcohol consumption, smoking, NYHA, and SBP. CONCLUSIONS Elderly patients with HF differed from younger patients in terms of long-term outcome and prognostic factors. There were also important differences within the elderly group itself. FAU - Ozieranski, Krzysztof AU - Ozieranski K FAU - Balsam, Pawel AU - Balsam P FAU - Tyminska, Agata AU - Tyminska A FAU - Peller, Michal AU - Peller M FAU - Kaplon-Cieslicka, Agnieszka AU - Kaplon-Cieslicka A FAU - Marchel, Michal AU - Marchel M FAU - Drozdz, Jaroslaw AU - Drozdz J FAU - Filipiak, Krzysztof J AU - Filipiak KJ FAU - Opolski, Grzegorz AU - Opolski G LA - eng PT - Journal Article DEP - 20160811 PL - Poland TA - Pol Arch Med Wewn JT - Polskie Archiwum Medycyny Wewnetrznej JID - 0401225 SB - IM CIN - Pol Arch Med Wewn. 2016 Aug 25;126(7-8):463-4. PMID: 27578218 MH - Age Factors MH - Aged MH - Aged, 80 and over MH - Blood Pressure MH - Coronary Disease MH - Exercise MH - Female MH - Heart Failure/*diagnosis/mortality MH - Humans MH - Male MH - Middle Aged MH - Poland/epidemiology MH - Prognosis MH - Pulmonary Disease, Chronic Obstructive MH - Registries MH - Renal Insufficiency, Chronic MH - Risk Factors EDAT- 2016/08/12 06:00 MHDA- 2017/03/28 06:00 CRDT- 2016/08/12 06:00 PHST- 2016/08/12 06:00 [entrez] PHST- 2016/08/12 06:00 [pubmed] PHST- 2017/03/28 06:00 [medline] AID - 10.20452/pamw.3490 [doi] PST - ppublish SO - Pol Arch Med Wewn. 2016 Aug 11;126(7-8):502-13. doi: 10.20452/pamw.3490. Epub 2016 Aug 11.