PMID- 27513497 OWN - NLM STAT- MEDLINE DCOM- 20171004 LR - 20181023 IS - 1699-5198 (Electronic) IS - 0212-1611 (Linking) VI - 33 IP - 3 DP - 2016 Jun 30 TI - [Not Available]. PG - 270 LID - 10.20960/nh.270 [doi] AB - BACKGROUND: Heart failure (HF) patients develop important changes in body composition, but only a small number of studies have evaluated the associations between these changes and functional class deterioration in a prospective manner. OBJECTIVE: The aim of this study was to evaluate whether changes in bioimpedance parameters were associated with NYHA functional class deterioration over six months. METHODS: A total of 275 chronic stable HF patients confirmed by echocardiography were recruited. Body composition measurements were obtained by whole body bioelectrical impedance with multiple frequency equipment (BodyStat QuadScan 4000). We evaluated functional class using the New York Heart Association (NYHA) classification at baseline and after six months. RESULTS: According to our results, 66 (24%) subjects exhibited functional class deterioration, while 209 improved or exhibited no change. A greater proportion of patients exhibited higher extracellular water (> 5%), and these patients developed hypervolemia, according to location on the resistance/reactance graph. A 5% decrease in resistance/height was associated with functional class deterioration with an OR of 1.42 (95% CI 1.01-2.0, p = 0.04). CONCLUSIONS: Body composition assessment through bioelectrical impedance exhibited a valuable performance as a marker of functional class deterioration in stable HF patients. FAU - Castillo-Martinez, Lilia AU - Castillo-Martinez L AD - Heart Failure Clinic and Clinical Nutrition Department. Instituto Nacional de Ciencias Medicas y Nutricion "Salvador Zubiran". Mexico City, Mexico. cam7125@gmail.com. FAU - Santillan-Diaz, Cira AU - Santillan-Diaz C FAU - Orea-Tejeda, Arturo AU - Orea-Tejeda A FAU - Gomez-Martinez, Manuel A AU - Gomez-Martinez MA FAU - Bernal-Ceballos, Fernanda AU - Bernal-Ceballos F FAU - Lozada-Mellado, Mariel AU - Lozada-Mellado M LA - spa PT - Journal Article TT - Body composition changes assessed by bioelectrical impedance and their associations with functional class deterioration in stable heart failure patients. DEP - 20160630 PL - Spain TA - Nutr Hosp JT - Nutricion hospitalaria JID - 9100365 SB - IM MH - Aged MH - Aged, 80 and over MH - *Body Composition MH - Disease Progression MH - *Electric Impedance MH - Extravascular Lung Water/metabolism MH - Female MH - Heart Failure/classification/diagnostic imaging/*pathology MH - Humans MH - Longitudinal Studies MH - Male MH - Middle Aged MH - Prospective Studies OTO - NOTNLM OT - Bioelectrical impedance analyses. Functional class deterioration. Heart failure. EDAT- 2016/08/12 06:00 MHDA- 2017/10/05 06:00 CRDT- 2016/08/12 06:00 PHST- 2016/06/30 00:00 [received] PHST- 2016/06/30 00:00 [accepted] PHST- 2016/08/12 06:00 [entrez] PHST- 2016/08/12 06:00 [pubmed] PHST- 2017/10/05 06:00 [medline] AID - 10.20960/nh.270 [doi] PST - epublish SO - Nutr Hosp. 2016 Jun 30;33(3):270. doi: 10.20960/nh.270.