PMID- 27513980
OWN - NLM
STAT- MEDLINE
DCOM- 20170314
LR  - 20191210
IS  - 1872-6968 (Electronic)
IS  - 0303-8467 (Linking)
VI  - 149
DP  - 2016 Oct
TI  - Lower cervical levels: Increased risk of early dysphonia following anterior 
      cervical spine surgery.
PG  - 118-21
LID - S0303-8467(16)30284-0 [pii]
LID - 10.1016/j.clineuro.2016.07.030 [doi]
AB  - OBJECTIVES: The present study aimed to re-evaluate the incidence of early 
      dysphonia after anterior cervical spine surgery (ACSS) and to determine the 
      related risk factors. CLINICAL MATERIALS AND METHODS: Patients underwent ACSS 
      between January 2011 and December 2013 at two sites were identified 
      retrospectively from hospital's patient databases. A total of 233 cases were 
      included in this study. Dysphonia developed 1 month postoperatively was recorded. 
      Follow-up was conducted in all positive-response patients. Those reporting severe 
      or persistent voice symptoms were referred to otolaryngologists for further 
      assessments and (or) treatments. Pre and intraoperative factors were collected to 
      determine their relationships with dysphonia one month postoperatively. RESULTS: 
      45 patients developed dysphonia at one month, including 23 males and 22 females, 
      yielding to an incidence of 19.3%. 34 cases resolved themselves in 3 months, 
      leaving the remaining 11 patients considered to be severe or persistent cases. 
      However, 10 of them recovered spontaneously in the next 9 months, while the last 
      case received vocal cord medialization and returned to almost normal speech 
      function at 18 months. In univariate analysis, only approaching level involving 
      C6-C7 or (and) C7-T1 was significantly associated with postoperative dysphonia 
      (P<0.001). This association was not weakened in multiple logistic regression 
      analysis (OR 2.348, 95% CI 1.467-3.659, P<0.001). CONCLUSION: The incidence of 
      early dysphonia following ACSS was relatively high and approaching at lower 
      cervical levels was an independent predictive factor.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Zeng, Ji-Huan
AU  - Zeng JH
AD  - Department of Orthopaedics, Jiangxi Province People's Hospital, Nanchang, 330006, 
      China.
FAU - Li, Xiao-Dan
AU  - Li XD
AD  - School of Nursing, Jiangxi Health Vocational College, Nanchang, 330052, China.
FAU - Deng, Liang
AU  - Deng L
AD  - Department of Orthopaedics, Jiangxi Province People's Hospital, Nanchang, 330006, 
      China.
FAU - Xiao, Qiang
AU  - Xiao Q
AD  - Department of Orthopaedics, Jiangxi Province People's Hospital, Nanchang, 330006, 
      China. Electronic address: kyxq168@126.com.
LA  - eng
PT  - Journal Article
DEP - 20160801
PL  - Netherlands
TA  - Clin Neurol Neurosurg
JT  - Clinical neurology and neurosurgery
JID - 7502039
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cervical Vertebrae/*surgery
MH  - Dysphonia/*etiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neurosurgical Procedures/adverse effects/*methods
MH  - *Outcome and Process Assessment, Health Care
MH  - Postoperative Complications/*etiology
MH  - Retrospective Studies
MH  - Spinal Diseases/*surgery
MH  - Young Adult
OTO - NOTNLM
OT  - Anterior cervical spine surgery
OT  - Early dysphonia
OT  - Lower cervical levels
EDAT- 2016/08/16 06:00
MHDA- 2017/03/16 06:00
CRDT- 2016/08/12 06:00
PHST- 2016/06/05 00:00 [received]
PHST- 2016/07/28 00:00 [revised]
PHST- 2016/07/31 00:00 [accepted]
PHST- 2016/08/12 06:00 [entrez]
PHST- 2016/08/16 06:00 [pubmed]
PHST- 2017/03/16 06:00 [medline]
AID - S0303-8467(16)30284-0 [pii]
AID - 10.1016/j.clineuro.2016.07.030 [doi]
PST - ppublish
SO  - Clin Neurol Neurosurg. 2016 Oct;149:118-21. doi: 10.1016/j.clineuro.2016.07.030. 
      Epub 2016 Aug 1.