PMID- 27527759
OWN - NLM
STAT- MEDLINE
DCOM- 20170421
LR  - 20220316
IS  - 1873-2542 (Electronic)
IS  - 0378-1135 (Linking)
VI  - 192
DP  - 2016 Aug 30
TI  - Factors associated with herd-level PRRSV infection and age-time to seroconversion 
      in farrow-to-finish herds.
PG  - 10-20
LID - S0378-1135(16)30161-4 [pii]
LID - 10.1016/j.vetmic.2016.06.006 [doi]
AB  - Factors associated with porcine reproductive and respiratory syndrome virus 
      (PRRSV) infection were investigated in 109 herds. Serums from four batches of 
      pigs (4, 10, 16 and 22 weeks, 15 pigs/batch) were tested by ELISA for PRRSV 
      antibodies. Infection by Mycoplasma hyopneumoniae (Mhp), Actinobacillus 
      pleuropneumoniae, H1N1 and H1N2 swine influenza A viruses (swIAV) and PCV2 were 
      detected by specific serological or PCR tests. Data related to herd 
      characteristics, biosecurity, management housing and climatic conditions were 
      collected during a herd visit. Factors associated with the herd's PRRSV 
      seropositive status were identified by logistic regression. Large herd size, the 
      lack of disinsectisation in the gestation facilities, on-farm semen collection, a 
      short time-period for gilt quarantine and a low temperature setpoint for the 
      ventilation controller in the fattening room significantly increased the odds of 
      a herd being seropositive for PRRSV. Infection by Mhp and H1N2 swIAV were 
      associated with a PRRSV seropositive status. A Cox proportional hazards model was 
      used to identify the factors associated with the age-time to seroconversion in 
      infected herds. Joint housing for the gilts and sows when lactating, a large 
      nursery pen, a small number of pens per fattening room and lack of all-in all-out 
      management in the fattening section significantly reduced the age-time to 
      seroconversion. A small range of temperatures controlling ventilation rate in the 
      nursery room was also associated with time to PRRSV seroconversion. Infection by 
      Mhp and a high PCV2 infection pressure were associated with a shorter time to 
      seroconversion. Biosecurity measures minimising the risk of introducing PRRSV 
      into the herd, management practices reducing contacts between animals from 
      different batches and within batches and favourable climatic conditions should be 
      implemented to better control PRRSV infection.
CI  - Copyright (c) 2016. Published by Elsevier B.V.
FAU - Fablet, C
AU  - Fablet C
AD  - Agence Nationale de Securite Sanitaire (Anses), Unite Epidemiologie et Bien-Etre 
      du Porc, B.P. 53, 22440 Ploufragan, France; Universite Bretagne Loire, 
      Ploufragan, France. Electronic address: christelle.fablet@anses.fr.
FAU - Marois-Crehan, C
AU  - Marois-Crehan C
AD  - Agence Nationale de Securite Sanitaire (Anses), Unite Mycoplasmologie 
      Bacteriologie, B.P. 53, 22440 Ploufragan, France; Universite Bretagne Loire, 
      Ploufragan, France.
FAU - Grasland, B
AU  - Grasland B
AD  - Agence Nationale de Securite Sanitaire (Anses), Unite Genetique Virale et 
      Biosecurite, B.P. 53, 22440 Ploufragan, France; Universite Bretagne Loire, 
      Ploufragan, France.
FAU - Simon, G
AU  - Simon G
AD  - Agence Nationale de Securite Sanitaire (Anses), Unite Virologie Immunologie 
      Porcines, B.P. 53, 22440 Ploufragan, France; Universite Bretagne Loire, 
      Ploufragan, France.
FAU - Rose, N
AU  - Rose N
AD  - Agence Nationale de Securite Sanitaire (Anses), Unite Epidemiologie et Bien-Etre 
      du Porc, B.P. 53, 22440 Ploufragan, France; Universite Bretagne Loire, 
      Ploufragan, France.
LA  - eng
PT  - Journal Article
DEP - 20160616
PL  - Netherlands
TA  - Vet Microbiol
JT  - Veterinary microbiology
JID - 7705469
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - *Aging
MH  - Animal Husbandry
MH  - Animals
MH  - Antibodies, Viral/*blood
MH  - Female
MH  - Helminthiasis, Animal
MH  - Porcine Reproductive and Respiratory Syndrome/blood/*epidemiology
MH  - Risk Factors
MH  - Seroconversion/*physiology
MH  - Swine
OTO - NOTNLM
OT  - Logistic regression
OT  - PRRS
OT  - Risk factors
OT  - Survival analysis
EDAT- 2016/08/17 06:00
MHDA- 2017/04/22 06:00
CRDT- 2016/08/17 06:00
PHST- 2016/03/14 00:00 [received]
PHST- 2016/05/04 00:00 [revised]
PHST- 2016/06/15 00:00 [accepted]
PHST- 2016/08/17 06:00 [entrez]
PHST- 2016/08/17 06:00 [pubmed]
PHST- 2017/04/22 06:00 [medline]
AID - S0378-1135(16)30161-4 [pii]
AID - 10.1016/j.vetmic.2016.06.006 [doi]
PST - ppublish
SO  - Vet Microbiol. 2016 Aug 30;192:10-20. doi: 10.1016/j.vetmic.2016.06.006. Epub 
      2016 Jun 16.