PMID- 27530189
OWN - NLM
STAT- MEDLINE
DCOM- 20170410
LR  - 20181202
IS  - 1522-726X (Electronic)
IS  - 1522-1946 (Linking)
VI  - 88
IP  - 2
DP  - 2016 Aug
TI  - Optimal anticoagulation prior to cath: Bivalirudin vs. Heparin the saga 
      continues....
PG  - 182-3
LID - 10.1002/ccd.26670 [doi]
AB  - During the pre-procedural (medication) phase, the use of bivalirudin monotherapy 
      is associated with the lowest rate of bleeding in patients with Non-ST elevation 
      myocardial infarction (Non-STEMI) undergoing an early invasive strategy. 
      Monotherapy with either bivalirudin or unfractionated heparin (UFH) appear 
      interchangeable in this setting. The use of GPI upstream with either drug should 
      be discouraged due to an increased risk of bleeding and net adverse events. The 
      use of low dose aspirin plus potent P2Y12 inhibitors followed by a transradial 
      approach with implantation of drug-eluting coronary stents with fluorinated 
      polymers represents an strategy that may help limit perioperative ischemic and 
      hemorrhagic complications in these individuals.
CI  - (c) 2016 Wiley Periodicals, Inc.
FAU - Belardi, Jorge A
AU  - Belardi JA
AD  - Department of Interventional Cardiology and Endovascular Therapeutics, Instituto 
      Cardiovascular De Buenos Aires, Ciudad Autonoma De Buenos Aires, Argentina.
FAU - Albertal, Mariano
AU  - Albertal M
AD  - Department of Interventional Cardiology and Endovascular Therapeutics, Instituto 
      Cardiovascular De Buenos Aires, Ciudad Autonoma De Buenos Aires, Argentina.
LA  - eng
PT  - Comment
PT  - Editorial
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the 
      Society for Cardiac Angiography & Interventions
JID - 100884139
RN  - 0 (Hirudins)
RN  - 0 (Peptide Fragments)
RN  - 0 (Platelet Glycoprotein GPIIb-IIIa Complex)
RN  - 0 (Recombinant Proteins)
RN  - 9005-49-6 (Heparin)
SB  - IM
CON - Catheter Cardiovasc Interv. 2016 Aug;88(2):174-81. PMID: 26332193
MH  - Hemorrhage/chemically induced
MH  - *Heparin
MH  - Hirudins
MH  - Humans
MH  - Peptide Fragments
MH  - Percutaneous Coronary Intervention
MH  - Platelet Glycoprotein GPIIb-IIIa Complex/*therapeutic use
MH  - Recombinant Proteins/therapeutic use
MH  - Treatment Outcome
OTO - NOTNLM
OT  - acute coronary syndromes
OT  - bivalirudin
OT  - medication phase
OT  - percutaneous coronary interventions
OT  - unfractionated heparin
EDAT- 2016/08/18 06:00
MHDA- 2017/04/11 06:00
CRDT- 2016/08/18 06:00
PHST- 2016/07/01 00:00 [received]
PHST- 2016/07/02 00:00 [accepted]
PHST- 2016/08/18 06:00 [entrez]
PHST- 2016/08/18 06:00 [pubmed]
PHST- 2017/04/11 06:00 [medline]
AID - 10.1002/ccd.26670 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2016 Aug;88(2):182-3. doi: 10.1002/ccd.26670.