PMID- 27536090 OWN - NLM STAT- MEDLINE DCOM- 20170807 LR - 20220316 IS - 1178-2005 (Electronic) IS - 1176-9106 (Print) IS - 1176-9106 (Linking) VI - 11 DP - 2016 TI - A simple and rapid test of physical performance inchronic obstructive pulmonary disease. PG - 1785-91 LID - 10.2147/COPD.S106151 [doi] AB - Impaired physical performance is common in chronic obstructive pulmonary disease (COPD), but its assessment can be difficult in routine clinical practice. We compared the timed up and go (TUG) test and other easily applied assessments of physical performance with the 6-minute walk distance (6MWD). In a longitudinal study of comorbidities in COPD, submaximal physical performance was determined in 520 patients and 150 controls using the TUG test and 6MWD. Spirometry, body composition, handgrip strength, the COPD assessment test, St George's Respiratory Questionnaire (SGRQ), and the modified Medical Research Council dyspnoea scale were also determined. Patients and controls were similar in age, body mass index, and sex proportions. The TUG in the patients was greater than that in the control group, P=0.001, and was inversely related to 6MWD (r=-0.71, P<0.001) and forced expiratory volume in one second predicted (r=-0.19, P<0.01) and was directly related to the SGRQ activity (r=0.39, P<0.001), SGRQ total (r=0.37, P<0.001), and total COPD assessment test scores (r=0.37, P<0.001). The TUG identified the difference in physical performance between patients and controls. The TUG test and validated questionnaires provide a measure of physical performance, which is rapid and could be used in clinical practice. FAU - Albarrati, Ali Mufraih AU - Albarrati AM AD - Physiotherapy Department, School of Healthcare Sciences, University Hospital of Wales, Cardiff University, Cardiff, UK. FAU - Gale, Nichola S AU - Gale NS AD - Physiotherapy Department, School of Healthcare Sciences, University Hospital of Wales, Cardiff University, Cardiff, UK. FAU - Enright, Stephanie AU - Enright S AD - Physiotherapy Department, School of Healthcare Sciences, University Hospital of Wales, Cardiff University, Cardiff, UK. FAU - Munnery, Margaret M AU - Munnery MM AD - Cardiorespiratory Medicine Department, Cardio-Respiratory Medicine, Wales Heart Research Institute, Cardiff University, University Hospital of Wales, Cardiff, UK. FAU - Cockcroft, John R AU - Cockcroft JR AD - Cardiorespiratory Medicine Department, Cardio-Respiratory Medicine, Wales Heart Research Institute, Cardiff University, University Hospital of Wales, Cardiff, UK. FAU - Shale, Dennis J AU - Shale DJ AD - Cardiorespiratory Medicine Department, Cardio-Respiratory Medicine, Wales Heart Research Institute, Cardiff University, University Hospital of Wales, Cardiff, UK. LA - eng PT - Comparative Study PT - Journal Article DEP - 20160802 PL - New Zealand TA - Int J Chron Obstruct Pulmon Dis JT - International journal of chronic obstructive pulmonary disease JID - 101273481 SB - IM MH - Age Factors MH - Aged MH - Area Under Curve MH - Body Composition MH - Case-Control Studies MH - Cross-Sectional Studies MH - Dyspnea/etiology/physiopathology MH - *Exercise Tolerance MH - Female MH - Geriatric Assessment/*methods MH - Hand Strength MH - Humans MH - Longitudinal Studies MH - Lung/*physiopathology MH - Male MH - Middle Aged MH - Predictive Value of Tests MH - Prognosis MH - Pulmonary Disease, Chronic Obstructive/complications/*diagnosis/physiopathology MH - ROC Curve MH - Reproducibility of Results MH - Severity of Illness Index MH - Spirometry MH - Surveys and Questionnaires MH - Time Factors MH - *Walk Test PMC - PMC4976811 OTO - NOTNLM OT - COPD OT - physical inactivity OT - timed up and go test EDAT- 2016/08/19 06:00 MHDA- 2017/08/08 06:00 PMCR- 2016/08/02 CRDT- 2016/08/19 06:00 PHST- 2016/08/19 06:00 [entrez] PHST- 2016/08/19 06:00 [pubmed] PHST- 2017/08/08 06:00 [medline] PHST- 2016/08/02 00:00 [pmc-release] AID - copd-11-1785 [pii] AID - 10.2147/COPD.S106151 [doi] PST - epublish SO - Int J Chron Obstruct Pulmon Dis. 2016 Aug 2;11:1785-91. doi: 10.2147/COPD.S106151. eCollection 2016.