PMID- 27536703
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160818
LR  - 20200930
IS  - 2322-3480 (Print)
IS  - 2322-3480 (Electronic)
IS  - 2322-3480 (Linking)
VI  - 4
IP  - 2
DP  - 2016 Apr
TI  - Sensitivity Comparison of the Skin Prick Test and Serum and Fecal Radio 
      Allergosorbent Test (RAST) in Diagnosis of Food Allergy in Children.
PG  - 98-103
AB  - BACKGROUND: Diagnosis of food allergy is difficult in children. Food allergies 
      are diagnosed using several methods that include medical histories, clinical 
      examinations, skin prick and serum-specific immunoglobulin E (IgE) tests, 
      radio-allergosorbent test (RAST), food challenge, and supervised elimination 
      diets. In this study we evaluated allergies to cow's milk, egg, peanut, and fish 
      in children with suspected food allergies with skin prick tests and serum and 
      feces RAST. METHODS: Forty-one children with clinical symptoms of food allergies 
      were enrolled in the study. Skin prick tests and serum and fecal RAST were 
      performed and compared with challenge tests. RESULTS: The most common sites of 
      food allergy symptoms were gastrointestinal (82.9%) and skin (48.8%). 100% of the 
      patients responded to the challenge tests with cow's milk, egg, peanut, and fish. 
      65% of the patients tested positive with the skin prick test, 12.1% tested 
      positive with serum RAST, and 29.2% tested positive with fecal RAST. CONCLUSION: 
      The skin prick test was more sensitive than serum or fecal RAST, and fecal RAST 
      was more than twice as sensitive as serum RAST.
FAU - Kianifar, Hamid Reza
AU  - Kianifar HR
AD  - Allergy Research Center, School of Medicine, Mashhad University of Medical 
      Sciences, Mashhad, Iran; Clinical Research Development Center, Ghaem Hospital, 
      School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
FAU - Pourreza, Alireza
AU  - Pourreza A
AD  - Allergy Research Center, School of Medicine, Mashhad University of Medical 
      Sciences, Mashhad, Iran.
FAU - Jabbari Azad, Farahzad
AU  - Jabbari Azad F
AD  - Allergy Research Center, School of Medicine, Mashhad University of Medical 
      Sciences, Mashhad, Iran.
FAU - Yousefzadeh, Hadis
AU  - Yousefzadeh H
AD  - Student Research Committee, School of Medicine, Mashhad University of Medical 
      Sciences, Mashhad, Iran.
FAU - Masomi, Fatemeh
AU  - Masomi F
AD  - Allergy Research Center, School of Medicine, Mashhad University of Medical 
      Sciences, Mashhad, Iran.
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - Rep Biochem Mol Biol
JT  - Reports of biochemistry & molecular biology
JID - 101637937
PMC - PMC4986269
OTO - NOTNLM
OT  - Food Hypersensitivity
OT  - Radioallergosorbent test
OT  - Sensitivity
OT  - Specificity
EDAT- 2016/08/19 06:00
MHDA- 2016/08/19 06:01
PMCR- 2016/04/01
CRDT- 2016/08/19 06:00
PHST- 2016/08/19 06:00 [entrez]
PHST- 2016/08/19 06:00 [pubmed]
PHST- 2016/08/19 06:01 [medline]
PHST- 2016/04/01 00:00 [pmc-release]
AID - rbmb-4-098 [pii]
PST - ppublish
SO  - Rep Biochem Mol Biol. 2016 Apr;4(2):98-103.