PMID- 27540095 OWN - NLM STAT- MEDLINE DCOM- 20171201 LR - 20221207 IS - 2044-6055 (Electronic) IS - 2044-6055 (Linking) VI - 6 IP - 8 DP - 2016 Aug 18 TI - Vitamin D deficiency in Malaysian adolescents aged 13 years: findings from the Malaysian Health and Adolescents Longitudinal Research Team study (MyHeARTs). PG - e010689 LID - 10.1136/bmjopen-2015-010689 [doi] LID - e010689 AB - OBJECTIVE: To determine the prevalence of vitamin D deficiency (<37.5 nmol/L) among young adolescents in Malaysia and its association with demographic characteristics, anthropometric measures and physical activity. DESIGN: This is a cross-sectional study among Form 1 (year 7) students from 15 schools selected using a stratified random sampling design. Information regarding sociodemographic characteristics, clinical data and environmental factors was collected and blood samples were taken for total vitamin D. Descriptive and multivariable logistic regression was performed on the data. SETTING: National secondary schools in Peninsular Malaysia. PARTICIPANTS: 1361 students (mean age 12.9+/-0.3 years) (61.4% girls) completed the consent forms and participated in this study. Students with a chronic health condition and/or who could not understand the questionnaires due to lack of literacy were excluded. MAIN OUTCOME MEASURES: Vitamin D status was determined through measurement of sera 25-hydroxyvitamin D (25(OH)D). Body mass index (BMI) was classified according to International Obesity Task Force (IOTF) criteria. Self-reported physical activity levels were assessed using the validated Malay version of the Physical Activity Questionnaire for Older Children (PAQ-C). RESULTS: Deficiency in vitamin D was seen in 78.9% of the participants. The deficiency was significantly higher in girls (92.6%, p<0.001), Indian adolescents (88.6%, p<0.001) and urban-living adolescents (88.8%, p<0.001). Females (OR=8.98; 95% CI 6.48 to 12.45), adolescents with wider waist circumference (OR=2.64; 95% CI 1.65 to 4.25) and in urban areas had higher risks (OR=3.57; 95% CI 2.54 to 5.02) of being vitamin D deficient. CONCLUSIONS: The study shows a high prevalence of vitamin D deficiency among young adolescents. Main risk factors are gender, ethnicity, place of residence and obesity. CI - Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ FAU - Al-Sadat, Nabilla AU - Al-Sadat N AD - Faculty of Medicine, Centre for Population Health (CePH), University of Malaya, Kuala Lumpur, Malaysia Faculty of Medicine, Department of Social and Preventive Medicine, University of Malaya, Kuala Lumpur, Malaysia. FAU - Majid, Hazreen Abdul AU - Majid HA AD - Faculty of Medicine, Centre for Population Health (CePH), University of Malaya, Kuala Lumpur, Malaysia Faculty of Medicine, Department of Social and Preventive Medicine, University of Malaya, Kuala Lumpur, Malaysia. FAU - Sim, Pei Ying AU - Sim PY AD - Faculty of Medicine, Centre for Population Health (CePH), University of Malaya, Kuala Lumpur, Malaysia. FAU - Su, Tin Tin AU - Su TT AD - Faculty of Medicine, Centre for Population Health (CePH), University of Malaya, Kuala Lumpur, Malaysia Faculty of Medicine, Department of Social and Preventive Medicine, University of Malaya, Kuala Lumpur, Malaysia. FAU - Dahlui, Maznah AU - Dahlui M AD - Faculty of Medicine, Centre for Population Health (CePH), University of Malaya, Kuala Lumpur, Malaysia Faculty of Medicine, Department of Social and Preventive Medicine, University of Malaya, Kuala Lumpur, Malaysia. FAU - Abu Bakar, Mohd Fadzrel AU - Abu Bakar MF AD - Faculty of Medicine, Centre for Population Health (CePH), University of Malaya, Kuala Lumpur, Malaysia. FAU - Dzaki, Najat AU - Dzaki N AD - Faculty of Medicine, Centre for Population Health (CePH), University of Malaya, Kuala Lumpur, Malaysia. FAU - Norbaya, Saidatul AU - Norbaya S AD - Family Health Development Division, Ministry of Health Malaysia, Putrajaya, Malaysia. FAU - Murray, Liam AU - Murray L AD - Centre for Public Health, Queen's University Belfast, Royal Victoria Hospital, Belfast, UK. FAU - Cantwell, Marie M AU - Cantwell MM AD - Centre for Public Health, Queen's University Belfast, Royal Victoria Hospital, Belfast, UK. FAU - Jalaludin, Muhammad Yazid AU - Jalaludin MY AD - Faculty of Medicine, Department of Paediatrics, University of Malaya, Kuala Lumpur, Malaysia. CN - MyHeART study group LA - eng PT - Journal Article DEP - 20160818 PL - England TA - BMJ Open JT - BMJ open JID - 101552874 RN - 1406-16-2 (Vitamin D) RN - A288AR3C9H (25-hydroxyvitamin D) SB - IM MH - Adolescent MH - Asian People MH - Body Mass Index MH - Cross-Sectional Studies MH - *Exercise MH - Female MH - Humans MH - Logistic Models MH - Longitudinal Studies MH - Malaysia/epidemiology MH - Male MH - Obesity/*epidemiology MH - Prevalence MH - Self Report MH - Sex Distribution MH - Sex Factors MH - Vitamin D/*analogs & derivatives/blood MH - Vitamin D Deficiency/*epidemiology PMC - PMC5013370 OTO - NOTNLM OT - PREVENTIVE MEDICINE OT - PUBLIC HEALTH OT - SOCIAL MEDICINE EDAT- 2016/08/20 06:00 MHDA- 2017/12/02 06:00 PMCR- 2016/08/18 CRDT- 2016/08/20 06:00 PHST- 2016/08/20 06:00 [entrez] PHST- 2016/08/20 06:00 [pubmed] PHST- 2017/12/02 06:00 [medline] PHST- 2016/08/18 00:00 [pmc-release] AID - bmjopen-2015-010689 [pii] AID - 10.1136/bmjopen-2015-010689 [doi] PST - epublish SO - BMJ Open. 2016 Aug 18;6(8):e010689. doi: 10.1136/bmjopen-2015-010689.