PMID- 27543469 OWN - NLM STAT- MEDLINE DCOM- 20170522 LR - 20181113 IS - 2213-3763 (Electronic) IS - 0019-4832 (Print) IS - 0019-4832 (Linking) VI - 68 IP - 4 DP - 2016 Jul-Aug TI - Spontaneous coronary artery dissection: Case series and review of literature. PG - 480-5 LID - S0019-4832(15)00928-1 [pii] LID - 10.1016/j.ihj.2015.11.039 [doi] AB - AIM: Spontaneous coronary artery dissection (SCAD) is a less recognized cause of ST elevation myocardial infarction (STEMI) in clinical practice. The aim of this communication is to describe a case series in South Asian population and highlight on the long-term clinical outcomes on conservative management. METHODS: A retrospective analysis of data of five patients (6 instances) of SCAD managed in a tertiary care center during January 1994 to June 2015 was done. Clinical, angiographic, therapeutic, and follow-up data till end of June 2015 are analyzed. RESULTS: All patients were young (mean - 33 years) and predominantly male. Etiology of SCAD was diverse and included peripartum state, vigorous activity and atherosclerosis. Left anterior descending (LAD) coronary artery was predominantly involved and the majority had angiographic type 1 SCAD. Medical treatment provides excellent long-term benefits. Coronary stenting provided symptomatic benefit in a patient with favorable anatomy. CONCLUSIONS: Clinical recognition of SCAD is difficult. It should be suspected in peripartum state, young females and in presence of other precipitating factors. Coronary angiography is essential for establishing the diagnosis. Medical treatment provides favorable long-term survival. IMPLICATIONS AND PRACTICE: The awareness of SCAD is important for all clinicians involved in STEMI care. A prompt suspicion can avoid administration of thrombolytic therapy. Early coronary angiography will provide an accurate diagnosis and help in deciding appropriate therapy. Percutaneous intervention can be challenging. CI - Copyright (c) 2015 Cardiological Society of India. Published by Elsevier B.V. All rights reserved. FAU - Sharma, Satyavan AU - Sharma S AD - Professor and Head of Cardiology and Interventional Cardiologist, Department of Cardiology, Bombay Hospital and Bombay Hospital Institute of Medical Sciences, Mumbai, India. FAU - Raut, Nikhil AU - Raut N AD - Senior Registrar, Department of Cardiology, Bombay Hospital and Bombay Hospital Institute of Medical Sciences, Mumbai, India. Electronic address: nikhs85@gmail.com. FAU - Potdar, Anil AU - Potdar A AD - Honorary Cardiologist, Department of Cardiology, Bombay Hospital and Bombay Hospital Institute of Medical Sciences, Mumbai, India. LA - eng PT - Case Reports PT - Journal Article PT - Review DEP - 20160112 PL - India TA - Indian Heart J JT - Indian heart journal JID - 0374675 RN - Coronary Artery Dissection, Spontaneous SB - IM MH - Adolescent MH - Adult MH - Coronary Angiography MH - Coronary Vessel Anomalies/*diagnosis/surgery MH - Coronary Vessels/*diagnostic imaging MH - *Early Diagnosis MH - Electrocardiography MH - Female MH - Humans MH - Male MH - Percutaneous Coronary Intervention/*methods MH - Retrospective Studies MH - *Stents MH - Vascular Diseases/*congenital/diagnosis/surgery MH - Young Adult PMC - PMC4990736 OTO - NOTNLM OT - Coronary artery dissection OT - ST elevation myocardial infarction OT - Spontaneous coronary artery dissection EDAT- 2016/08/21 06:00 MHDA- 2017/05/23 06:00 PMCR- 2017/07/01 CRDT- 2016/08/21 06:00 PHST- 2015/09/08 00:00 [received] PHST- 2015/11/23 00:00 [revised] PHST- 2015/11/30 00:00 [accepted] PHST- 2016/08/21 06:00 [entrez] PHST- 2016/08/21 06:00 [pubmed] PHST- 2017/05/23 06:00 [medline] PHST- 2017/07/01 00:00 [pmc-release] AID - S0019-4832(15)00928-1 [pii] AID - 10.1016/j.ihj.2015.11.039 [doi] PST - ppublish SO - Indian Heart J. 2016 Jul-Aug;68(4):480-5. doi: 10.1016/j.ihj.2015.11.039. Epub 2016 Jan 12.