PMID- 27554230
OWN - NLM
STAT- MEDLINE
DCOM- 20170901
LR  - 20170901
IS  - 1532-8422 (Electronic)
IS  - 1053-0770 (Linking)
VI  - 30
IP  - 6
DP  - 2016 Dec
TI  - Smoking Cessation Can Reduce the Incidence of Postoperative Hypoxemia After 
      On-Pump Coronary Artery Bypass Grafting Surgery.
PG  - 1545-1549
LID - S1053-0770(16)30133-1 [pii]
LID - 10.1053/j.jvca.2016.05.011 [doi]
AB  - OBJECTIVES: To determine whether smoking cessation can reduce the incidence of 
      postoperative hypoxemia (POH) after on-pump coronary artery bypass grafting 
      (CABG) surgery. DESIGN: Prospective, single-center, observational study. SETTING: 
      Single-center university teaching hospital. PARTICIPANTS: The study comprised 300 
      patients undergoing on-pump CABG surgery who met the inclusion criteria. Patients 
      were divided into the following 3 groups according to smoking status: sustained 
      quitters (n = 132)-smoking cessation for more than 1 month and less than 1 year; 
      quitters (n = 95)-smoking cessation for more than 1 week and less than 1 month; 
      and smokers (n = 73)-smoking at least 1 cigarette per day for at least 1 year. 
      INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: The primary outcome was the 
      incidence of POH after on-pump CABG surgery. Secondary outcomes included length 
      of postoperative mechanical ventilation and intensive care unit stay between the 
      POH group and non-POH group. There were significant decreases of POH incidence in 
      the sustained quitters and quitters compared with the smokers both after 
      intensive care unit (ICU) admission and 24 hours after surgery (18.2%, 18.9%, v 
      32.9%; p = 0.036 and 9.8%, 10.5%, v 26%; p = 0.003, respectively), and there was 
      no significant difference in POH incidence between the sustained quitters and 
      quitters. The length of postoperative mechanical ventilation was longer in 
      smokers than in sustained quitters and quitters (15.9+/-6.1 h v 11.9+/-5.3 h and 
      13.0+/-5.8 h, respectively; p<0.05), but there were no significant differences in 
      the length of ICU stay among the 3 groups (54.2+/-7.5 h v 55.1+/-7.5 h and 53.7+/-6.6 
      h, respectively; p = 0.333). CONCLUSIONS: Smoking cessation can reduce POH after 
      on-pump CABG surgery, and it also can shorten the length of postoperative 
      mechanical ventilation.
CI  - Copyright A(c) 2016 Elsevier Inc. All rights reserved.
FAU - Guan, Zheng
AU  - Guan Z
AD  - Departments of *Anesthesiology and. Electronic address: guanzheng1980@126.com.
FAU - Lv, Yi
AU  - Lv Y
AD  - Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, 
      Xi'an, Shaanxi, China.
FAU - Liu, Jingjie
AU  - Liu J
AD  - Department of Neurology, Second Affiliated Hospital of Xi'an Jiaotong University, 
      Xi'an, Shaanxi, China.
FAU - Liu, Lin
AU  - Liu L
AD  - Departments of *Anesthesiology and.
FAU - Yuan, Hui
AU  - Yuan H
AD  - Departments of *Anesthesiology and.
FAU - Shen, Xin
AU  - Shen X
AD  - Departments of *Anesthesiology and.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20160511
PL  - United States
TA  - J Cardiothorac Vasc Anesth
JT  - Journal of cardiothoracic and vascular anesthesia
JID - 9110208
SB  - IM
MH  - *Coronary Artery Bypass
MH  - Female
MH  - Humans
MH  - Hypoxia/*prevention & control
MH  - Incidence
MH  - Length of Stay/statistics & numerical data
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/*prevention & control
MH  - Prospective Studies
MH  - Smoking Cessation/*statistics & numerical data
OTO - NOTNLM
OT  - coronary artery bypass grafting
OT  - postoperative hypoxemia
OT  - smoking cessation
EDAT- 2016/08/25 06:00
MHDA- 2017/09/02 06:00
CRDT- 2016/08/25 06:00
PHST- 2016/02/04 00:00 [received]
PHST- 2016/08/25 06:00 [pubmed]
PHST- 2017/09/02 06:00 [medline]
PHST- 2016/08/25 06:00 [entrez]
AID - S1053-0770(16)30133-1 [pii]
AID - 10.1053/j.jvca.2016.05.011 [doi]
PST - ppublish
SO  - J Cardiothorac Vasc Anesth. 2016 Dec;30(6):1545-1549. doi: 
      10.1053/j.jvca.2016.05.011. Epub 2016 May 11.