PMID- 27557798
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20180427
LR  - 20240325
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 6
DP  - 2016 Aug 25
TI  - Gain-loss asymmetry in neural correlates of temporal discounting: An 
      approach-avoidance motivation perspective.
PG  - 31902
LID - 10.1038/srep31902 [doi]
LID - 31902
AB  - Gain-loss asymmetry in temporal discounting (i.e., when individuals discount 
      gains more than losses) has been implicated in numerous problematic and addictive 
      behaviors, resulting in enormous personal and societal costs. On the basis of 
      findings from a previous study, we speculated that approach-avoidance motivation 
      would modulate gain-loss asymmetry. To test this speculation, we examined the 
      effects of motivation on gain-loss asymmetry by analyzing functional 
      connectivity. We found that approach and avoidance motivation were negatively 
      associated with functional connectivity between the medial orbitofrontal cortex 
      (MOFC) and the dorsolateral prefrontal cortex and functional connectivity between 
      the MOFC and the posterior parietal cortex (PPC) in the gain domain. Only 
      avoidance motivation was found to be positively associated with functional 
      connectivity between the medial prefrontal cortex (MPFC) and the posterior 
      cingulate cortex (PCC) as well as between the MPFC and the insula in the loss 
      domain. Our findings suggest that the relationships of approach-avoidance 
      motivation and neural correlates yielded an asymmetrical pattern between the gain 
      and loss domains in temporal discounting. Thus, we provide new insight into 
      understanding gain-loss asymmetry in temporal discounting.
FAU - Zhang, Yang-Yang
AU  - Zhang YY
AD  - Key Laboratory of Behavioral Sciences &Magnetic Resonance Imaging Research 
      Center, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, 
      China.
AD  - University of Chinese Academy of Sciences, Beijing, 100039, China.
FAU - Xu, Lijuan
AU  - Xu L
AD  - National Laboratory of Pattern Recognition, Institute of Automation, Chinese 
      Academy of Sciences, Beijing, 100190, China.
FAU - Rao, Li-Lin
AU  - Rao LL
AD  - Key Laboratory of Behavioral Sciences &Magnetic Resonance Imaging Research 
      Center, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, 
      China.
FAU - Zhou, Lei
AU  - Zhou L
AD  - Key Laboratory of Behavioral Sciences &Magnetic Resonance Imaging Research 
      Center, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, 
      China.
AD  - University of Chinese Academy of Sciences, Beijing, 100039, China.
FAU - Zhou, Yuan
AU  - Zhou Y
AD  - Key Laboratory of Behavioral Sciences &Magnetic Resonance Imaging Research 
      Center, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, 
      China.
AD  - University of Chinese Academy of Sciences, Beijing, 100039, China.
FAU - Jiang, Tianzi
AU  - Jiang T
AD  - National Laboratory of Pattern Recognition, Institute of Automation, Chinese 
      Academy of Sciences, Beijing, 100190, China.
AD  - Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, 
      Beijing, 100190, China.
AD  - Key Laboratory for NeuroInformation of the Ministry of Education, School of Life 
      Science and Technology, University of Electronic Science and Technology of China, 
      Chengdu, 625014, China.
FAU - Li, Shu
AU  - Li S
AD  - Key Laboratory of Behavioral Sciences &Magnetic Resonance Imaging Research 
      Center, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, 
      China.
FAU - Liang, Zhu-Yuan
AU  - Liang ZY
AD  - Key Laboratory of Behavioral Sciences &Magnetic Resonance Imaging Research 
      Center, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, 
      China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160825
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
PMC - PMC4997255
COIS- The authors declare no competing financial interests.
EDAT- 2016/08/26 06:00
MHDA- 2016/08/26 06:01
PMCR- 2016/08/25
CRDT- 2016/08/26 06:00
PHST- 2016/01/05 00:00 [received]
PHST- 2016/07/26 00:00 [accepted]
PHST- 2016/08/26 06:00 [entrez]
PHST- 2016/08/26 06:00 [pubmed]
PHST- 2016/08/26 06:01 [medline]
PHST- 2016/08/25 00:00 [pmc-release]
AID - srep31902 [pii]
AID - 10.1038/srep31902 [doi]
PST - epublish
SO  - Sci Rep. 2016 Aug 25;6:31902. doi: 10.1038/srep31902.