PMID- 27562898
OWN - NLM
STAT- MEDLINE
DCOM- 20171207
LR  - 20220409
IS  - 1878-3279 (Electronic)
IS  - 0171-2985 (Linking)
VI  - 222
IP  - 2
DP  - 2017 Feb
TI  - Cord and blood levels of newborn IgE: Correlation, role and influence of maternal 
      IgE.
PG  - 450-453
LID - S0171-2985(16)30345-X [pii]
LID - 10.1016/j.imbio.2016.08.004 [doi]
AB  - The role of cord blood immunoglobulin E (IgE) levels in predicting the 
      development of atopy has been widely investigated. The aim of the study was to 
      evaluate the correlation between serum and cord blood total IgE in newborns and 
      the possible influence of the atopic status of the mother on them. It was also 
      investigated the possible role of gestational age on neonatal total IgE levels. 
      We considered 763 deliveries, 724>/=37 weeks of gestation and 39<37 weeks of 
      gestation. 14% of mothers (13.7% at term, 15.4% preterm) showed high total IgE 
      levels. The results showed a significant correlation between serum and cord IgE 
      levels both in preterm and term newborns. The data revealed also that mother's 
      total IgE levels affect both neonatal serum and cord total IgE levels. For the 
      latters we also found child gender as an additional independent predictor. On the 
      contrary total IgE levels are not affected by gestational age. Clinical 
      limitations of total IgE is known but their determination can be useful to define 
      atopy and to suggest follow-up of the children.
CI  - Copyright (c) 2016 Elsevier GmbH. All rights reserved.
FAU - De Amici, M
AU  - De Amici M
AD  - Department of Paediatrics, Foundation IRCCS Policlinico San Matteo, University of 
      Pavia, Pavia, Italy. Electronic address: m.deamici@smatteo.pv.it.
FAU - Perotti, F
AU  - Perotti F
AD  - Department of Maternal and Children's Health, Obstetrics and Gynecology Unit, 
      Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
FAU - Marseglia, G L
AU  - Marseglia GL
AD  - Department of Paediatrics, Foundation IRCCS Policlinico San Matteo, University of 
      Pavia, Pavia, Italy.
FAU - Ierullo, A M
AU  - Ierullo AM
AD  - Department of Maternal and Children's Health, Obstetrics and Gynecology Unit, 
      Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
FAU - Bollani, L
AU  - Bollani L
AD  - Department of Maternal and Children's Health, Neonatal Intensive Care Unit, 
      Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
FAU - Decembrino, L
AU  - Decembrino L
AD  - Department of Maternal and Children's Health, Neonatal Intensive Care Unit, 
      Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
FAU - Licari, A
AU  - Licari A
AD  - Department of Paediatrics, Foundation IRCCS Policlinico San Matteo, University of 
      Pavia, Pavia, Italy.
FAU - Quaglini, S
AU  - Quaglini S
AD  - Department of Electrical, Computer and Biomedical Engineering, University of 
      Pavia, Italy.
FAU - Stronati, M
AU  - Stronati M
AD  - Department of Maternal and Children's Health, Neonatal Intensive Care Unit, 
      Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
FAU - Spinillo, A
AU  - Spinillo A
AD  - Department of Maternal and Children's Health, Obstetrics and Gynecology Unit, 
      Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
LA  - eng
PT  - Journal Article
DEP - 20160809
PL  - Netherlands
TA  - Immunobiology
JT  - Immunobiology
JID - 8002742
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Female
MH  - Fetal Blood/*immunology
MH  - Gestational Age
MH  - Humans
MH  - *Immunity, Maternally-Acquired
MH  - Immunoglobulin E/*blood/*immunology
MH  - Infant, Newborn
MH  - Male
MH  - Mothers
MH  - Odds Ratio
MH  - Pregnancy
OTO - NOTNLM
OT  - Gestational age
OT  - Pregnance
OT  - Total IgE
EDAT- 2016/08/27 06:00
MHDA- 2017/12/08 06:00
CRDT- 2016/08/27 06:00
PHST- 2015/11/27 00:00 [received]
PHST- 2016/07/11 00:00 [revised]
PHST- 2016/08/05 00:00 [accepted]
PHST- 2016/08/27 06:00 [pubmed]
PHST- 2017/12/08 06:00 [medline]
PHST- 2016/08/27 06:00 [entrez]
AID - S0171-2985(16)30345-X [pii]
AID - 10.1016/j.imbio.2016.08.004 [doi]
PST - ppublish
SO  - Immunobiology. 2017 Feb;222(2):450-453. doi: 10.1016/j.imbio.2016.08.004. Epub 
      2016 Aug 9.