PMID- 27573062 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20180427 LR - 20190112 IS - 2045-2322 (Electronic) IS - 2045-2322 (Linking) VI - 6 DP - 2016 Aug 30 TI - Non-stick syringe needles: Beneficial effects of thin film metallic glass coating. PG - 31847 LID - 10.1038/srep31847 [doi] LID - 31847 AB - This paper reports on the use of Zr-based (Zr53Cu33Al9Ta5) thin film metallic glass (TFMG) for the coating of syringe needles and compares the results with those obtained using titanium nitride and pure titanium coatings. TFMG coatings were shown to reduce insertion forces by approximately 66% and retraction forces by approximately 72%, when tested using polyurethane rubber block. The benefits of TFMG-coated needles were also observed when tested using muscle tissue from pigs. In nano-scratch tests, the TFMG coatings achieved a coefficient of friction (COF) of just approximately 0.05, which is about one order of magnitude lower than those of other coatings. Finite-element modeling also indicates a significant reduction in injection and retraction forces. The COF can be attributed to the absence of grain boundaries in the TFMG coating as well as a smooth surface morphology and low surface free energy. FAU - Chu, Jinn P AU - Chu JP AD - Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan. FAU - Yu, Chia-Chi AU - Yu CC AD - Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan. FAU - Tanatsugu, Yusuke AU - Tanatsugu Y AD - Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan. AD - Department of Chemical Science and Technology, Tokushima University, Tokushima 770-8506, Japan. FAU - Yasuzawa, Mikito AU - Yasuzawa M AD - Department of Chemical Science and Technology, Tokushima University, Tokushima 770-8506, Japan. FAU - Shen, Yu-Lin AU - Shen YL AD - Department of Mechanical Engineering, University of New Mexico, Albuquerque, NM 87131, USA. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20160830 PL - England TA - Sci Rep JT - Scientific reports JID - 101563288 PMC - PMC5004157 EDAT- 2016/08/31 06:00 MHDA- 2016/08/31 06:01 PMCR- 2016/08/30 CRDT- 2016/08/31 06:00 PHST- 2016/05/16 00:00 [received] PHST- 2016/07/27 00:00 [accepted] PHST- 2016/08/31 06:00 [entrez] PHST- 2016/08/31 06:00 [pubmed] PHST- 2016/08/31 06:01 [medline] PHST- 2016/08/30 00:00 [pmc-release] AID - srep31847 [pii] AID - 10.1038/srep31847 [doi] PST - epublish SO - Sci Rep. 2016 Aug 30;6:31847. doi: 10.1038/srep31847.