PMID- 27580547
OWN - NLM
STAT- MEDLINE
DCOM- 20170228
LR  - 20181202
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Linking)
VI  - 55
IP  - 17
DP  - 2016
TI  - Antineutrophil Cytoplasmic Antibody-associated Vasculitis Superimposed on 
      Infection-related Glomerulonephritis Secondary to Pulmonary Mycobacterium avium 
      Complex Infection.
PG  - 2439-45
LID - 10.2169/internalmedicine.55.6588 [doi]
AB  - A 73-year-old woman was diagnosed with pulmonary Mycobacterium avium complex 
      (MAC) infection and received no treatment. Disease progression was evident one 
      year later with the development of myeloperoxidase-antineutrophil cytoplasmic 
      antibody (ANCA) titers and systemic symptoms of a fever, polyarthritis, purpura, 
      and rapidly progressive glomerulonephritis. Her symptoms did not improve with 
      antibiotic treatment. A renal biopsy revealed crescentic glomerulonephritis with 
      immunodeposition. According to these findings, she was diagnosed with 
      ANCA-associated vasculitis (AAV) superimposed on infection-related 
      glomerulonephritis (IRGN). Although there was a risk of aggravating an underlying 
      infection, the combination therapy of corticosteroid and antibiotics improved 
      AAV, IRGN, and even the lung radiological findings. To the best of our knowledge, 
      this is the first case of AAV and IRGN secondary to pulmonary MAC infection.
FAU - Asano, Shuichi
AU  - Asano S
AD  - Department of Respiratory Medicine, Nagoya University Graduate School of 
      Medicine, Japan.
FAU - Mizuno, Shige
AU  - Mizuno S
FAU - Okachi, Shotaro
AU  - Okachi S
FAU - Aso, Hiromichi
AU  - Aso H
FAU - Wakahara, Keiko
AU  - Wakahara K
FAU - Hashimoto, Naozumi
AU  - Hashimoto N
FAU - Ito, Satoru
AU  - Ito S
FAU - Kozaki, Yohei
AU  - Kozaki Y
FAU - Katsuno, Takayuki
AU  - Katsuno T
FAU - Maruyama, Shoichi
AU  - Maruyama S
FAU - Hasegawa, Yoshinori
AU  - Hasegawa Y
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20160901
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
RN  - 0 (Adrenal Cortex Hormones)
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Adrenal Cortex Hormones/therapeutic use
MH  - Aged
MH  - Anti-Bacterial Agents/therapeutic use
MH  - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/*etiology
MH  - Disease Progression
MH  - Female
MH  - Glomerulonephritis/*etiology/microbiology
MH  - Humans
MH  - Mycobacterium avium-intracellulare Infection/*complications/drug therapy
MH  - Pneumonia, Bacterial/*complications/drug therapy/microbiology
EDAT- 2016/09/02 06:00
MHDA- 2017/03/01 06:00
CRDT- 2016/09/02 06:00
PHST- 2016/09/02 06:00 [entrez]
PHST- 2016/09/02 06:00 [pubmed]
PHST- 2017/03/01 06:00 [medline]
AID - 10.2169/internalmedicine.55.6588 [doi]
PST - ppublish
SO  - Intern Med. 2016;55(17):2439-45. doi: 10.2169/internalmedicine.55.6588. Epub 2016 
      Sep 1.