PMID- 27582492
OWN - NLM
STAT- MEDLINE
DCOM- 20170503
LR  - 20170503
IS  - 1938-2707 (Electronic)
IS  - 0009-9228 (Linking)
VI  - 55
IP  - 11
DP  - 2016 Oct
TI  - Cow's Milk Protein Allergy.
PG  - 1054-63
LID - 10.1177/0009922816664512 [doi]
AB  - Cow's milk protein allergy (CMPA) is a common condition encountered in children 
      with incidence estimated as 2% to 7.5% in the first year of life. Formula and 
      breast-fed babies can present with symptoms of CMPA. It is important to 
      accurately diagnose CMPA to avoid the consequences of either under- or 
      overdiagnosis. CMPA is classically categorized into immunoglobulin E (IgE)- or 
      non-IgE-mediated reaction that vary in clinical manifestations, diagnostic 
      evaluation, and prognosis. The most commonly involved systems in patients with 
      CMPA are gastrointestinal, skin, and respiratory. Evaluation of CMPA starts with 
      good data gathering followed by testing if indicated. Treatment is simply by 
      avoidance of cow's milk protein (CMP) in the child's or mother's diet, if 
      exclusively breast-feeding. This article reviews the definition, epidemiology, 
      risk factors, pathogenesis, clinical presentation, evaluation, management, and 
      prognosis of CMPA and provides an overview of different options for formulas and 
      their indication in the treatment of CMPA.
CI  - (c) The Author(s) 2016.
FAU - Mousan, Grace
AU  - Mousan G
AD  - Children's Hospital of Michigan, Detroit, MI, USA gmousanyazigi@gmail.com.
FAU - Kamat, Deepak
AU  - Kamat D
AD  - Children's Hospital of Michigan, Detroit, MI, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20160831
PL  - United States
TA  - Clin Pediatr (Phila)
JT  - Clinical pediatrics
JID - 0372606
SB  - IM
MH  - Humans
MH  - Infant
MH  - Milk Hypersensitivity/*diagnosis/physiopathology/*therapy
MH  - Risk Factors
OTO - NOTNLM
OT  - Allergic colitis
OT  - allergy
OT  - amino-acid based formula
OT  - breast-feeding
OT  - cow's milk
OT  - elimination diet
OT  - extensively hydrolyzed formula
OT  - formula feeding
OT  - oral challenge
OT  - protein
EDAT- 2016/09/02 06:00
MHDA- 2017/05/04 06:00
CRDT- 2016/09/02 06:00
PHST- 2016/09/02 06:00 [entrez]
PHST- 2016/09/02 06:00 [pubmed]
PHST- 2017/05/04 06:00 [medline]
AID - 0009922816664512 [pii]
AID - 10.1177/0009922816664512 [doi]
PST - ppublish
SO  - Clin Pediatr (Phila). 2016 Oct;55(11):1054-63. doi: 10.1177/0009922816664512. 
      Epub 2016 Aug 31.