PMID- 27594873
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160905
LR  - 20200929
IS  - 1671-5411 (Print)
IS  - 1671-5411 (Linking)
VI  - 13
IP  - 5
DP  - 2016 Jul
TI  - Improvements in quality of life in septuagenarians versus octogenarians 
      undergoing trans-catheter aortic valve replacement.
PG  - 439-43
LID - 10.11909/j.issn.1671-5411.2016.05.006 [doi]
AB  - BACKGROUND: Very elderly patients represent a distinct patient group in clinical 
      setting in terms of a decision for trans-catheter aortic valve replacement (TAVR) 
      when one considers the potential improvement in the quality of life (QoL) on one 
      hand and the benefit to risk ratio on the other. This study aimed to compare 
      functional and QoL outcomes of TAVR between octogenarians and septuagenarians. 
      METHODS: This prospective cohort study included 136 elderly patients (70 to 89 
      years of age), who underwent transfemoral TAVR due to degenerative aortic 
      stenosis. Patients were allocated into one of the following age groups: 
      septuagenarians (n = 67) and octogenarians (n = 69). Preoperative and early 
      postoperative clinical parameters were recorded. In addition, QoL of the patients 
      was evaluated using SF-36 questionnaire preoperatively and six month 
      postoperatively. RESULTS: Groups were similar in terms of early postoperative 
      mortality and morbidity parameters. The mean New York Heart Association (NYHA) 
      class improved after TAVR in both groups. In addition, all SF-36 norm-based scale 
      and SF-36 summary scale scores improved significantly in both groups during the 
      postoperative period. Postoperatively, physical functioning, general health and 
      physical component summary scores were significantly better in the septuagenarian 
      group (P = 0.02, 0.01, 0.03, respectively). CONCLUSION: Although the improvement 
      in the QoL in terms of physical health was more marked in septuagenarians than in 
      octogenarians, substantial benefits on the QoL and particularly on mental health 
      seem to justify re-consideration of TAVR indications in the very elderly.
FAU - Ay, Nuray Kahraman
AU  - Ay NK
AD  - Department of Cardiology, Bezmialem Vakif University, Fatih, Istanbul, Turkey.
FAU - Ay, Yasin
AU  - Ay Y
AD  - Department of Cardiovascular Surgery, Bezmialem Vakif University, Fatih, 
      Istanbul, Turkey.
FAU - Sonmez, Osman
AU  - Sonmez O
AD  - Department of Cardiology, Bezmialem Vakif University, Fatih, Istanbul, Turkey.
FAU - Vatankulu, Mehmet Akif
AU  - Vatankulu MA
AD  - Department of Cardiology, Bezmialem Vakif University, Fatih, Istanbul, Turkey.
FAU - Goktekin, Omer
AU  - Goktekin O
AD  - Department of Cardiology, Bezmialem Vakif University, Fatih, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
PL  - China
TA  - J Geriatr Cardiol
JT  - Journal of geriatric cardiology : JGC
JID - 101237881
PMC - PMC4984562
OTO - NOTNLM
OT  - Elderly
OT  - Octogenarians
OT  - Quality of life
OT  - Septuagenarian
OT  - Trans-catheter aortic valve replacement
EDAT- 2016/09/07 06:00
MHDA- 2016/09/07 06:01
PMCR- 2016/07/01
CRDT- 2016/09/06 06:00
PHST- 2016/09/06 06:00 [entrez]
PHST- 2016/09/07 06:00 [pubmed]
PHST- 2016/09/07 06:01 [medline]
PHST- 2016/07/01 00:00 [pmc-release]
AID - jgc-13-05-439 [pii]
AID - 10.11909/j.issn.1671-5411.2016.05.006 [doi]
PST - ppublish
SO  - J Geriatr Cardiol. 2016 Jul;13(5):439-43. doi: 
      10.11909/j.issn.1671-5411.2016.05.006.