PMID- 27603273
OWN - NLM
STAT- MEDLINE
DCOM- 20180914
LR  - 20210824
IS  - 2329-9185 (Electronic)
IS  - 2329-9185 (Linking)
VI  - 4
IP  - 8
DP  - 2016 Aug 30
TI  - Molecular Markers in Bone and Soft-Tissue Tumors.
LID - e5 [pii]
LID - 10.2106/JBJS.RVW.15.00092 [doi]
AB  - Many sarcomas such as osteosarcoma have complex molecular compositions and 
      behaviors that make standardized treatment difficult for patients with these 
      tumors. Chromosomal translocations are noted in specific bone and soft-tissue 
      sarcomas, and there are molecular tests (polymerase chain reaction [PCR] and 
      fluorescence in situ hybridization [FISH]) used for accurate diagnosis. The 
      translocations noted in sarcomas may allow future therapeutic targeting.
FAU - Wustrack, Rosanna
AU  - Wustrack R
AD  - University of California, San Francisco, San Francisco, California.
FAU - Cooper, Kumarasen
AU  - Cooper K
AD  - Departments of Pathology (K.C.) and Orthopaedic Surgery (K.W.), University of 
      Pennsylvania, Philadelphia, Pennsylvania.
FAU - Weber, Kristy
AU  - Weber K
AD  - Departments of Pathology (K.C.) and Orthopaedic Surgery (K.W.), University of 
      Pennsylvania, Philadelphia, Pennsylvania.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - JBJS Rev
JT  - JBJS reviews
JID - 101674872
RN  - 0 (Biomarkers, Tumor)
SB  - IM
MH  - Biomarkers, Tumor/*analysis
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Polymerase Chain Reaction
MH  - Sarcoma
MH  - Soft Tissue Neoplasms/*diagnosis
MH  - Translocation, Genetic
EDAT- 2016/09/08 06:00
MHDA- 2018/09/15 06:00
CRDT- 2016/09/08 06:00
PHST- 2016/09/08 06:00 [entrez]
PHST- 2016/09/08 06:00 [pubmed]
PHST- 2018/09/15 06:00 [medline]
AID - 01874474-201608000-00005 [pii]
AID - 10.2106/JBJS.RVW.15.00092 [doi]
PST - ppublish
SO  - JBJS Rev. 2016 Aug 30;4(8):e5. doi: 10.2106/JBJS.RVW.15.00092.