PMID- 27603578
OWN - NLM
STAT- MEDLINE
DCOM- 20170703
LR  - 20180209
IS  - 1097-4598 (Electronic)
IS  - 0148-639X (Linking)
VI  - 55
IP  - 1
DP  - 2017 Jan
TI  - Contraction mode and whey protein intake affect the synthesis rate of 
      intramuscular connective tissue.
PG  - 128-130
LID - 10.1002/mus.25398 [doi]
AB  - INTRODUCTION: In this study we investigated the impact of whey protein 
      hydrolysate and maltodextrin (WPH) intake on intramuscular connective tissue 
      (IMCT) protein fractional synthesis rate (FSR) after maximal shortening and 
      lengthening contractions. METHODS: Twenty young men were randomized to receive 
      either WPH or maltodextrin [carbohydrate (CHO)] immediately after completion of 
      unilateral shortening and lengthening knee extensions. Ring-(13) C(6) 
      -phenylalanine was infused, and muscle biopsies were obtained. IMCT protein FSR 
      was measured at 1-5, as well as 1-3 and 3-5 hours after contractions and nutrient 
      intake. RESULTS: During the 1-3-hour recovery, lengthening contractions resulted 
      in a higher FSR than shortening contractions (P < 0.01), independent of 
      supplementation type and, during the 3-5-hour recovery, WPH had a higher FSR than 
      CHO (P < 0.05), independent of prior contraction mode. CONCLUSIONS: The later 
      appearance of a stimulating effect of WPH on the IMCT FSR after strenuous muscle 
      contractions lends support to its ability to promote recovery of the muscle 
      connective tissue matrix after exercise. Muscle Nerve 55: 128-130, 2017.
CI  - (c) 2016 Wiley Periodicals, Inc.
FAU - Holm, Lars
AU  - Holm L
AD  - Institute of Sports Medicine, Department of Orthopedic Surgery M, Bispebjerg 
      Hospital, Copenhagen, Denmark.
AD  - Department of Biomedical Sciences, Faculty of Health and Medical Sciences, 
      University of Copenhagen, Copenhagen, Denmark.
FAU - Rahbek, Stine Klejs
AU  - Rahbek SK
AD  - Section for Sport Science, Department of Public Health, Aarhus University, 
      Aarhus, Denmark.
FAU - Farup, Jean
AU  - Farup J
AD  - Section for Sport Science, Department of Public Health, Aarhus University, 
      Aarhus, Denmark.
FAU - Vendelbo, Mikkel Holm
AU  - Vendelbo MH
AD  - Department of Internal Medicine and Endocrinology, Aarhus University Hospital, 
      Aarhus, Denmark.
AD  - Department of Nuclear Medicine and PET Center, Aarhus University Hospital, 
      Aarhus, Denmark.
FAU - Vissing, Kristian
AU  - Vissing K
AD  - Section for Sport Science, Department of Public Health, Aarhus University, 
      Aarhus, Denmark.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20160926
PL  - United States
TA  - Muscle Nerve
JT  - Muscle & nerve
JID - 7803146
RN  - 0 (Muscle Proteins)
RN  - 0 (Polysaccharides)
RN  - 0 (Whey Proteins)
RN  - 47E5O17Y3R (Phenylalanine)
RN  - 7CVR7L4A2D (maltodextrin)
SB  - IM
MH  - Adult
MH  - Analysis of Variance
MH  - Connective Tissue/*drug effects/*metabolism
MH  - Functional Laterality
MH  - Humans
MH  - Male
MH  - Muscle Contraction/physiology
MH  - Muscle Proteins/metabolism
MH  - Muscle, Skeletal/*cytology
MH  - Phenylalanine
MH  - Polysaccharides/*pharmacology
MH  - Whey Proteins/*biosynthesis/metabolism
MH  - Young Adult
OTO - NOTNLM
OT  - concentric contraction
OT  - eccentric contraction
OT  - fractional synthesis rate
OT  - milk protein
OT  - muscle collagen
OT  - resistance exercise
EDAT- 2016/09/08 06:00
MHDA- 2017/07/04 06:00
CRDT- 2016/09/08 06:00
PHST- 2016/09/02 00:00 [accepted]
PHST- 2016/09/08 06:00 [pubmed]
PHST- 2017/07/04 06:00 [medline]
PHST- 2016/09/08 06:00 [entrez]
AID - 10.1002/mus.25398 [doi]
PST - ppublish
SO  - Muscle Nerve. 2017 Jan;55(1):128-130. doi: 10.1002/mus.25398. Epub 2016 Sep 26.