PMID- 27604109 OWN - NLM STAT- MEDLINE DCOM- 20191125 LR - 20240130 IS - 1532-6551 (Electronic) IS - 1071-3581 (Linking) VI - 25 IP - 4 DP - 2018 Aug TI - Image fusion between 18F-FDG PET and MRI in cardiac sarcoidosis: A case series. PG - 1128-1134 LID - 10.1007/s12350-016-0653-6 [doi] AB - BACKGROUND: Sarcoidosis is a systemic disorder of unknown etiology. It is distinguished by the presence of noncaseating epithelioid granulomas. This study demonstrates the use of image fusion between (18)F-fluoro-2-deoxy-D-glucose positron emission tomography (18F-FDG PET) and magnetic resonance imaging (MRI) to diagnose patients with cardiac sarcoidosis (CS). METHODS: Seven patients diagnosed with sarcoidosis were retrospectively included. All patients underwent 18F-FDG PET/CT and cardiac MRI. RESULTS: On the MRI scan, late gadolinium enhancement (LGE) was observed in five patients. T2-weighted images revealed areas with an increased signal consistent with myocardial edema in two patients and with hypointensity suggesting fibrosis in one patient. Increased 18F-FDG uptake was seen in the myocardial wall in three patients, indicating active inflammation. CONCLUSION: 18F-FDG PET and MRI image fusion allows clinicians to obtain complete morphofunctional cartography in patients with sarcoidosis. Our data show that 18F-FDG PET/MRI image fusion imaging can be useful in the diagnosis of CS. FAU - Zandieh, Shahin AU - Zandieh S AD - Institute of Radiology and Nuclear Medicine, Hanusch Hospital, Teaching Hospital of Medical University of Vienna, Vienna, Austria. zandieh.s@icloud.com. FAU - Bernt, Reinhard AU - Bernt R AD - Institute of Radiology and Nuclear Medicine, Hanusch Hospital, Teaching Hospital of Medical University of Vienna, Vienna, Austria. FAU - Mirzaei, Siroos AU - Mirzaei S AD - Department of Nuclear Medicine with PET-center, Wilhelminenspital, Vienna, Austria. FAU - Haller, Joerg AU - Haller J AD - Institute of Radiology and Nuclear Medicine, Hanusch Hospital, Teaching Hospital of Medical University of Vienna, Vienna, Austria. FAU - Hergan, Klaus AU - Hergan K AD - Department of Radiology, Paracelsus Medical University of Salzburg, Salzburg, Austria. LA - eng PT - Journal Article DEP - 20160907 PL - United States TA - J Nucl Cardiol JT - Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology JID - 9423534 RN - 0 (Radiopharmaceuticals) RN - 0Z5B2CJX4D (Fluorodeoxyglucose F18) SB - IM EIN - J Nucl Cardiol. 2017 Feb 9;:. PMID: 28185231 MH - Aged MH - Cardiomyopathies/*diagnostic imaging MH - Female MH - *Fluorodeoxyglucose F18 MH - Humans MH - Magnetic Resonance Imaging/*methods MH - Male MH - Middle Aged MH - Multimodal Imaging/*methods MH - Positron Emission Tomography Computed Tomography/*methods MH - *Radiopharmaceuticals MH - Retrospective Studies MH - Sarcoidosis/*diagnostic imaging OTO - NOTNLM OT - 18F-FDG PET OT - Magnetic resonance imaging OT - cardiac sarcoidosis OT - image fusion EDAT- 2016/09/09 06:00 MHDA- 2019/11/26 06:00 CRDT- 2016/09/09 06:00 PHST- 2016/06/15 00:00 [received] PHST- 2016/08/11 00:00 [revised] PHST- 2016/09/09 06:00 [pubmed] PHST- 2019/11/26 06:00 [medline] PHST- 2016/09/09 06:00 [entrez] AID - S1071-3581(23)02315-2 [pii] AID - 10.1007/s12350-016-0653-6 [doi] PST - ppublish SO - J Nucl Cardiol. 2018 Aug;25(4):1128-1134. doi: 10.1007/s12350-016-0653-6. Epub 2016 Sep 7.