PMID- 27605764
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160908
LR  - 20200929
IS  - 0971-7196 (Print)
IS  - 0975-0703 (Electronic)
IS  - 0971-7196 (Linking)
VI  - 40
IP  - 3
DP  - 2016 Sep
TI  - In vitro studies on medicinal plants used against bacterial diabetic foot ulcer 
      (BDFU) and urinary tract infected (UTI) causing pathogens.
PG  - 667-73
LID - 10.1007/s12639-014-0555-y [doi]
AB  - The pus samples from diabetic foot ulcer patients and urine samples from urinary 
      tract infected patients were collected and inoculated in nutrient agar plates. 
      The colonies showing different morphologies were streaked on selective agar 
      plates. The antibacterial assay of selected commercial antibiotics was tested 
      against the foot ulcer and urinary tract isolates. The result revealed that most 
      of the organisms were found to be resistant against the antibiotics. Screening of 
      antibacterial activity of selected plants, methanol extracts of plants were 
      prepared and tested against foot ulcer pathogens. Among the plants used, the 
      methanolic extract Tragia involucrata was very effective against the foot ulcer 
      pathogens and to separate the compounds present in the methanolic extract of T. 
      involucrata, when it was subjected to column chromatography. The fractions 
      obtained were further checked for their antibacterial property and fraction 1 
      which inhibited the pathogens, were subjected to thin layer chromatography and 
      the structure of the particular phytochemical compound was elucidated by NMR 
      study. The spices were tested for their antibacterial property against the 
      urinary tract pathogens. Among the spices tested; Allium sativum inhibited the 
      growth of the pathogens isolated from urinary tract infection. It can be 
      concluded that the plants extract can be used to discover natural products that 
      may serve as lead for the development of new pharmaceuticals addressing the major 
      therapeutic needs.
FAU - Subbu Lakshmi, S
AU  - Subbu Lakshmi S
AD  - Department of Microbiology, Kamaraj College, Tuticorin, India.
FAU - Chelladurai, G
AU  - Chelladurai G
AD  - Department of Zoology, Kamaraj College, Tuticorin, India.
FAU - Suresh, B
AU  - Suresh B
AD  - Department of Chemistry, Kamaraj College, Tuticorin, India.
LA  - eng
PT  - Journal Article
DEP - 20140920
PL  - India
TA  - J Parasit Dis
JT  - Journal of parasitic diseases : official organ of the Indian Society for 
      Parasitology
JID - 9713059
PMC - PMC4996168
OTO - NOTNLM
OT  - Antibacterial activity
OT  - Chromatography
OT  - Medicinal plants and spices
OT  - NMR
EDAT- 2016/09/09 06:00
MHDA- 2016/09/09 06:01
PMCR- 2017/09/01
CRDT- 2016/09/09 06:00
PHST- 2014/07/08 00:00 [received]
PHST- 2014/08/28 00:00 [accepted]
PHST- 2016/09/09 06:00 [entrez]
PHST- 2016/09/09 06:00 [pubmed]
PHST- 2016/09/09 06:01 [medline]
PHST- 2017/09/01 00:00 [pmc-release]
AID - 555 [pii]
AID - 10.1007/s12639-014-0555-y [doi]
PST - ppublish
SO  - J Parasit Dis. 2016 Sep;40(3):667-73. doi: 10.1007/s12639-014-0555-y. Epub 2014 
      Sep 20.