PMID- 27606110 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160908 LR - 20181113 IS - 2075-051X (Print) IS - 2075-0528 (Electronic) IS - 2075-051X (Linking) VI - 16 IP - 3 DP - 2016 Aug TI - Impact of Body Mass Index on Vascular Calcification and Pericardial Fat Volume Among Patients with Suspected Coronary Artery Disease. PG - e310-6 LID - 10.18295/squmj.2016.16.03.008 [doi] AB - OBJECTIVES: This study aimed to assess the effect of body mass index (BMI) on the relationship between pericardial fat volume (PFV), aortic root calcification (ARC) and coronary artery calcification (CAC) among patients with suspected coronary artery disease (CAD). METHODS: This cross-sectional study took place between January and December 2014 at the Kufa University Teaching Hospital, Najaf, Iraq. A total of 130 consecutive patients with an intermediate pretest probability of ischaemic heart disease who underwent 64-slice multidetector computed tomography (CT) angiography during the study period were recruited. Of these, 111 were included in the study and divided into groups according to BMI. Imaging markers were measured on CT angiography. RESULTS: A total of 28 patients were obese, while 42 and 41 were overweight and normal weight, respectively. The median PFV, CAC and ARC was 109 cm(3) (interquartile range [IQR]: 52-176 cm(3)), 0 Agatston score (IQR: 0-52 Agatston score) and 0 Agatston score (IQR: 0-15 Agatston score), respectively, in the normal weight group in comparison to 79 cm(3) (IQR: 43-138 cm(3)), 0 Agatston score (IQR: 0-54 Agatston score) and 0 Agatston score (IQR: 0-0 Agatston score), respectively, in the obese group. Significant correlations were observed between PFV and CAC (r(2) = 0.22; P = 0.002) and ARC and CAC (r(2) = 0.37; P <0.001) in the normal weight group. However, no significant correlations were observed for obese and overweight patients. CONCLUSION: These findings indicate that BMI may not be an accurate tool for measuring adiposity or assessing subclinical coronary atherosclerosis in patients with suspected CAD. FAU - Nafakhi, Hussein AU - Nafakhi H AD - Department of Internal Medicine, Faculty of Medicine, University of Kufa, Najaf, Iraq. FAU - Al-Mosawi, Abdulameer AU - Al-Mosawi A AD - Department of Radiology, Faculty of Medicine, University of Kufa, Najaf, Iraq. FAU - Elwali, Hayder AU - Elwali H AD - Department of Radiology, Faculty of Medicine, University of Kufa, Najaf, Iraq. FAU - Al-Nafakh, Hasan AU - Al-Nafakh H AD - Department of Radiology, Faculty of Medicine, University of Kufa, Najaf, Iraq. FAU - Tawfeq, Raad AU - Tawfeq R AD - Department of Radiology, Almustansyria University, Baghdad, Iraq. FAU - Nafakhi, Ahmed AU - Nafakhi A AD - Department of Clinical Pharmacy, Najaf Health Bureau, Najaf, Iraq. LA - eng PT - Journal Article DEP - 20160819 PL - Oman TA - Sultan Qaboos Univ Med J JT - Sultan Qaboos University medical journal JID - 101519915 PMC - PMC4996293 OTO - NOTNLM OT - Atherosclerosis OT - Body Mass Index OT - Coronary Angiography OT - Coronary Vessels OT - Obesity OT - Pericardium OT - Vascular Calcification EDAT- 2016/09/09 06:00 MHDA- 2016/09/09 06:01 PMCR- 2016/08/01 CRDT- 2016/09/09 06:00 PHST- 2015/11/01 00:00 [received] PHST- 2016/01/25 00:00 [revised] PHST- 2016/02/14 00:00 [revised] PHST- 2016/02/28 00:00 [revised] PHST- 2016/03/23 00:00 [revised] PHST- 2016/04/07 00:00 [accepted] PHST- 2016/09/09 06:00 [entrez] PHST- 2016/09/09 06:00 [pubmed] PHST- 2016/09/09 06:01 [medline] PHST- 2016/08/01 00:00 [pmc-release] AID - squmj1608-e310-316 [pii] AID - 10.18295/squmj.2016.16.03.008 [doi] PST - ppublish SO - Sultan Qaboos Univ Med J. 2016 Aug;16(3):e310-6. doi: 10.18295/squmj.2016.16.03.008. Epub 2016 Aug 19.