PMID- 27607965 OWN - NLM STAT- MEDLINE DCOM- 20180131 LR - 20181023 IS - 1539-4794 (Electronic) IS - 0146-9592 (Linking) VI - 41 IP - 17 DP - 2016 Sep 1 TI - Estimation of optical rotation of chiral molecules with weak measurements. PG - 4032-5 LID - 10.1364/OL.41.004032 [doi] AB - From its beginning, the measurement of optical rotation (OR) is crucial for the analysis of chiral molecules in many fields. However, the precision measurement of a weak OR signal with conventional setup remains elusive. In this Letter, we experimentally propose a precision method to determine the OR of glucose and fructose based on weak measurements. By using the spin Hall effect of light (SHEL) as a probe, a nonlinear weak measurements model is established that is applicable beyond the Aharonov-Albert-Vaidman (AAV) limit. Due to the high sensitivity of weak measurements amplification with respect to the OR, a tremendous variation of the amplified beam displacement of the SHEL is observed, while the concentration of glucose and fructose is slightly changed. FAU - Qiu, Xiaodong AU - Qiu X FAU - Xie, Linguo AU - Xie L FAU - Liu, Xiong AU - Liu X FAU - Luo, Lan AU - Luo L FAU - Zhang, Zhiyou AU - Zhang Z FAU - Du, Jinglei AU - Du J LA - eng PT - Journal Article PL - United States TA - Opt Lett JT - Optics letters JID - 7708433 SB - IM MH - *Optical Rotation MH - *Stereoisomerism EDAT- 2016/09/09 06:00 MHDA- 2018/02/01 06:00 CRDT- 2016/09/09 06:00 PHST- 2016/09/09 06:00 [entrez] PHST- 2016/09/09 06:00 [pubmed] PHST- 2018/02/01 06:00 [medline] AID - 349006 [pii] AID - 10.1364/OL.41.004032 [doi] PST - ppublish SO - Opt Lett. 2016 Sep 1;41(17):4032-5. doi: 10.1364/OL.41.004032.