PMID- 27610156
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160909
LR  - 20231111
IS  - 1735-0328 (Print)
IS  - 1726-6890 (Electronic)
IS  - 1726-6882 (Linking)
VI  - 15
IP  - 1
DP  - 2016 Winter
TI  - Validation of an Analytical Method for Determination of 13 priority polycyclic 
      aromatic hydrocarbons in mineral water using dispersive liquid-liquid 
      microextraction and GC-MS.
PG  - 157-68
AB  - Dispersive liquid-liquid microextraction (DLLME) combined with gas 
      chromatography-mass spectrometry (GC-MS) was used for the extraction and 
      determination of 13 polycyclic aromatic hydrocarbons (PAHs) in mineral water 
      samples. In this procedure, the suitable combination of extraction solvent (500 
      microL chloroform) and disperser solvent (1000 microL acetone) were quickly injected into 
      the water sample (10.00 mL) by Hamilton syringe. After centrifugation, 500 microL of 
      the lower organic phase was dried under a gentle stream of nitrogen, re-dissolved 
      in chloroform and injected into GC-MS. Chloroform and acetone were found to be 
      the best extraction and disperser solvent, respectively. Validation of the method 
      was performed using spiked calibration curves. The enrichment factor ranged from 
      93 to 129 and the recovery ranged from 71 to 90%. The linear ranges for all the 
      PAHs were 0.10-2.80 ngmL(-1). The relative standard deviations (RSDs) of PAHs in 
      water by using anthracene-d10 as internal standard, were in the range of 4-11% 
      for most of the analytes (n = 3). Limit of detection (LOD) for different PAHs 
      were between 0.03 and 0.1 ngmL(-1). The method was successfully applied for the 
      analysis of PAHs in mineral water samples collected from Tehran.
FAU - Sadeghi, Ramezan
AU  - Sadeghi R
AD  - Department of Toxicology and Pharmacology, School of Pharmacy, Shahid Beheshti 
      University of Medical Sciences, Tehran, Iran. ; Department of Environmental 
      Health Engineering, School of Health, Shahrekord University of Medical sciences, 
      Shahrekord, Iran.
FAU - Kobarfard, Farzad
AU  - Kobarfard F
AD  - Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University 
      of Medical Sciences, Tehran, Iran. ; Phytochemistry Research Center, Shahid 
      Beheshti University of Medical Sciences, Tehran, Iran.
FAU - Yazdanpanah, Hassan
AU  - Yazdanpanah H
AD  - Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University 
      of Medical Sciences, Tehran, Iran. ; Department of Toxicology and Pharmacology, 
      School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
FAU - Eslamizad, Samira
AU  - Eslamizad S
AD  - Department of Toxicology and Pharmacology, School of Pharmacy, Shahid Beheshti 
      University of Medical Sciences, Tehran, Iran.
FAU - Bayat, Mitra
AU  - Bayat M
AD  - Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, 
      Tehran, Iran.
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Iran J Pharm Res
JT  - Iranian journal of pharmaceutical research : IJPR
JID - 101208407
PMC - PMC4986111
OTO - NOTNLM
OT  - Dispersive Liquid-Liquid Microextraction (DLLME)
OT  - GC-MS
OT  - Iran
OT  - Polycyclic aromatic hydrocarbons (PAHs)
OT  - mineral water
EDAT- 2016/09/10 06:00
MHDA- 2016/09/10 06:01
PMCR- 2016/01/01
CRDT- 2016/09/10 06:00
PHST- 2016/09/10 06:00 [entrez]
PHST- 2016/09/10 06:00 [pubmed]
PHST- 2016/09/10 06:01 [medline]
PHST- 2016/01/01 00:00 [pmc-release]
AID - ijpr-15-157 [pii]
PST - ppublish
SO  - Iran J Pharm Res. 2016 Winter;15(1):157-68.