PMID- 27614051
OWN - NLM
STAT- MEDLINE
DCOM- 20170525
LR  - 20220318
IS  - 1537-2995 (Electronic)
IS  - 0041-1132 (Linking)
VI  - 56
IP  - 11
DP  - 2016 Nov
TI  - Very low rate of patient-related adverse events associated with the use of 
      intraoperative cell salvage.
PG  - 2768-2772
LID - 10.1111/trf.13791 [doi]
AB  - BACKGROUND: The rate of patient-related clinical adverse events (AEs) associated 
      with the use of intraoperative cell salvage (ICS) was analyzed. STUDY DESIGN AND 
      METHODS: The perfusion service and electronic risk management databases in a 
      nine-hospital regional health care system were reviewed over an approximately 
      11-year period. The number of ICS cases performed during this period and basic 
      patient demographics were also extracted. RESULTS: There were 43,198 patients for 
      whom ICS was utilized during the study period. Recovered blood was returned to 
      33,351 (77.2%) patients. Electronic comments on the ICS procedure were found in 
      2348 of 33,351 (7.0%) cases. The vast majority of comments (2203/2348, 93.8%) 
      described minor events that did not lead to patient-related AEs such as the 
      surgeon requested higher than normal suction pressure or that no RBCs were 
      returned. Only 144 of 2348 (6.1%) of the comments described procedural or 
      equipment-related events or potential AEs. From these comments two potential AEs 
      were identified: the first was a post-Cesarean section patient who became acutely 
      tachycardic, hypertensive, and dyspneic with rigors. The second was a patient 
      with postpartum hemorrhage who experienced acute dyspnea and hypotension. Both 
      patients were rapidly stabilized and discharged from the hospital shortly 
      thereafter without further complications. It is unclear if these events were 
      caused by ICS reinfusion. No air emboli were reported. The overall rate of 
      patient-related AEs associated with ICS reinfusion was between 0 and 2 per 33,351 
      (0%-0.006%). CONCLUSIONS: The use of ICS is safe with a very low rate of 
      patient-related AEs.
CI  - (c) 2016 AABB.
FAU - DeAndrade, Diana
AU  - DeAndrade D
AD  - Department of Anesthesiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
FAU - Waters, Jonathan H
AU  - Waters JH
AUID- ORCID: 0000-0001-9057-6086
AD  - Department of Anesthesiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
AD  - Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania.
FAU - Triulzi, Darrell J
AU  - Triulzi DJ
AD  - Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.
AD  - The Institute for Transfusion Medicine, University of Pittsburgh Medical Center, 
      Pittsburgh, Pennsylvania.
FAU - Alarcon, Louis
AU  - Alarcon L
AD  - Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.
FAU - Wisniewski, Mary Kay
AU  - Wisniewski MK
AD  - Donald J. Wolff Quality Institute, University of Pittsburgh Medical Center, 
      Pittsburgh, Pennsylvania.
FAU - Dyga, Robert
AU  - Dyga R
AD  - UPMC Procirca, Pittsburgh, Pennsylvania.
FAU - Yazer, Mark H
AU  - Yazer MH
AD  - Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.
AD  - The Institute for Transfusion Medicine, University of Pittsburgh Medical Center, 
      Pittsburgh, Pennsylvania.
LA  - eng
PT  - Journal Article
DEP - 20160909
PL  - United States
TA  - Transfusion
JT  - Transfusion
JID - 0417360
SB  - IM
MH  - Databases, Factual
MH  - Humans
MH  - Operative Blood Salvage/*adverse effects
MH  - Patient Safety
MH  - Perfusion/adverse effects
MH  - Retrospective Studies
EDAT- 2016/09/11 06:00
MHDA- 2017/05/26 06:00
CRDT- 2016/09/11 06:00
PHST- 2016/06/02 00:00 [received]
PHST- 2016/07/13 00:00 [revised]
PHST- 2016/07/13 00:00 [accepted]
PHST- 2016/09/11 06:00 [pubmed]
PHST- 2017/05/26 06:00 [medline]
PHST- 2016/09/11 06:00 [entrez]
AID - 10.1111/trf.13791 [doi]
PST - ppublish
SO  - Transfusion. 2016 Nov;56(11):2768-2772. doi: 10.1111/trf.13791. Epub 2016 Sep 9.