PMID- 2763451 OWN - NLM STAT- MEDLINE DCOM- 19890908 LR - 20190824 IS - 0304-4017 (Print) IS - 0304-4017 (Linking) VI - 31 IP - 3-4 DP - 1989 Jun TI - Enzymes of oxidant defence system of leucocytes and erythrocytes in bovine anaplasmosis. PG - 333-7 AB - The glutathione oxidant defence system in leucocytes and erythrocytes of six Anaplasma marginale-infected calves was examined by assaying glutathione peroxidase (GSH-px), glutathione reductase (GSSG-R), reduced glutathione (GSH) and superoxide dismutase (SOD). In addition, GSH-S-transferase and arginase levels were measured in leucocytes. There was a significant decline in the activities of leucocyte GSH-px, GSSG-R and SOD in the post-patent period; whereas arginase activity rose significantly following the patent period of anaplasmosis. The activity of erythrocyte SOD declined in the post-patent stage. The infection also caused a decline in red cell GSH (P less than 0.05). The results suggest that the glutathione oxidant defence system of peripheral blood cells is significantly influenced by the Anaplasma infection. FAU - More, T AU - More T AD - Division of Biochemistry and Food Science, Indian Veterinary Research Institute, U.P., India. FAU - Reddy, G R AU - Reddy GR FAU - Sharma, S P AU - Sharma SP FAU - Singh, L N AU - Singh LN LA - eng PT - Journal Article PL - Netherlands TA - Vet Parasitol JT - Veterinary parasitology JID - 7602745 RN - EC 1.11.1.9 (Glutathione Peroxidase) RN - EC 1.15.1.1 (Superoxide Dismutase) RN - EC 1.8.1.7 (Glutathione Reductase) RN - EC 2.5.1.18 (Glutathione Transferase) RN - EC 3.5.3.1 (Arginase) RN - GAN16C9B8O (Glutathione) SB - IM MH - Anaplasmosis/*enzymology/immunology MH - Animals MH - Arginase/blood MH - Cattle MH - Cattle Diseases/*enzymology/immunology MH - Erythrocytes/*enzymology MH - Glutathione/blood MH - Glutathione Peroxidase/blood MH - Glutathione Reductase/blood MH - Glutathione Transferase/blood MH - Leukocytes/*enzymology MH - Male MH - Oxidation-Reduction MH - Superoxide Dismutase/blood EDAT- 1989/06/01 00:00 MHDA- 1989/06/01 00:01 CRDT- 1989/06/01 00:00 PHST- 1989/06/01 00:00 [pubmed] PHST- 1989/06/01 00:01 [medline] PHST- 1989/06/01 00:00 [entrez] AID - 0304-4017(89)90082-4 [pii] AID - 10.1016/0304-4017(89)90082-4 [doi] PST - ppublish SO - Vet Parasitol. 1989 Jun;31(3-4):333-7. doi: 10.1016/0304-4017(89)90082-4.