PMID- 27641995
OWN - NLM
STAT- MEDLINE
DCOM- 20170821
LR  - 20171205
IS  - 1872-6240 (Electronic)
IS  - 0006-8993 (Linking)
VI  - 1650
DP  - 2016 Nov 1
TI  - Inferior frontal gyrus links visual and motor cortices during a visuomotor 
      precision grip force task.
PG  - 252-266
LID - S0006-8993(16)30619-9 [pii]
LID - 10.1016/j.brainres.2016.09.011 [doi]
AB  - Coordination between vision and action relies on a fronto-parietal network that 
      receives visual and proprioceptive sensory input in order to compute motor 
      control signals. Here, we investigated with magnetoencephalography (MEG) which 
      cortical areas are functionally coupled on the basis of synchronization during 
      visuomotor integration. MEG signals were recorded from twelve healthy adults 
      while performing a unimanual visuomotor (VM) task and control conditions. The VM 
      task required the integration of pinch motor commands with visual sensory 
      feedback. By using a beamformer, we localized the neural activity in the 
      frequency range of 1-30Hz during the VM compared to rest. Virtual sensors were 
      estimated at the active locations. A multivariate autoregressive model was used 
      to estimate the power and coherence of estimated activity at the virtual sensors. 
      Event-related desynchronisation (ERD) during VM was observed in early visual 
      areas, the rostral part of the left inferior frontal gyrus (IFG), the right IFG, 
      the superior parietal lobules, and the left hand motor cortex (M1). Functional 
      coupling in the alpha frequency band bridged the regional activities observed in 
      motor and visual cortices (the start and the end points in the visuomotor loop) 
      through the left or right IFG. Coherence between the left IFG and left M1 
      correlated inversely with the task performance. Our results indicate that an 
      occipital-prefrontal-motor functional network facilitates the modulation of 
      instructed motor responses to visual cues. This network may supplement the 
      mechanism for guiding actions that is fully incorporated into the dorsal visual 
      stream.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Papadelis, Christos
AU  - Papadelis C
AD  - Laboratory of Functional Neuroimaging, Center for Mind/Brain Sciences (CIMeC), 
      University of Trento, Via delle Regole 101, 38123 Mattarello, Italy. Electronic 
      address: christos.papadelis@childrens.harvard.edu.
FAU - Arfeller, Carola
AU  - Arfeller C
AD  - MEG Center, University of Tubingen, Otfried-Muller-Str 47, 72076 Tubingen, 
      Germany.
FAU - Erla, Silvia
AU  - Erla S
AD  - Laboratory of Functional Neuroimaging, Center for Mind/Brain Sciences (CIMeC), 
      University of Trento, Via delle Regole 101, 38123 Mattarello, Italy; Biophysics 
      and Biosignals Lab, Department of Physics & Biotech, University of Trento, Via 
      delle Regole 101, 38123 Mattarello, Italy.
FAU - Nollo, Giandomenico
AU  - Nollo G
AD  - Biophysics and Biosignals Lab, Department of Physics & Biotech, University of 
      Trento, Via delle Regole 101, 38123 Mattarello, Italy.
FAU - Cattaneo, Luigi
AU  - Cattaneo L
AD  - Laboratory of Functional Neuroimaging, Center for Mind/Brain Sciences (CIMeC), 
      University of Trento, Via delle Regole 101, 38123 Mattarello, Italy.
FAU - Braun, Christoph
AU  - Braun C
AD  - Laboratory of Functional Neuroimaging, Center for Mind/Brain Sciences (CIMeC), 
      University of Trento, Via delle Regole 101, 38123 Mattarello, Italy; MEG Center, 
      University of Tubingen, Otfried-Muller-Str 47, 72076 Tubingen, Germany; Werner 
      Reichardt Centre for Integrative Neuroscience (CIN) at the University of 
      Tubingen, Otfried-Muller-Str. 25, 72076 Tubingen, Germany.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160915
PL  - Netherlands
TA  - Brain Res
JT  - Brain research
JID - 0045503
SB  - IM
MH  - Adult
MH  - Brain Mapping/methods
MH  - Evoked Potentials/physiology
MH  - Female
MH  - Functional Laterality/physiology
MH  - Hand/physiology
MH  - Hand Strength
MH  - Humans
MH  - Magnetoencephalography/*methods
MH  - Male
MH  - Motor Cortex/physiology
MH  - Movement/physiology
MH  - Parietal Lobe/physiology
MH  - Prefrontal Cortex/metabolism/*physiology
MH  - Psychomotor Performance/physiology
MH  - Visual Cortex/physiology
OTO - NOTNLM
OT  - Coherence
OT  - Functional connectivity
OT  - Inferior frontal gyrus
OT  - Magnetoencephalography
OT  - Visuomotor integration
EDAT- 2016/09/20 06:00
MHDA- 2017/08/22 06:00
CRDT- 2016/09/20 06:00
PHST- 2016/04/22 00:00 [received]
PHST- 2016/09/06 00:00 [revised]
PHST- 2016/09/07 00:00 [accepted]
PHST- 2016/09/20 06:00 [pubmed]
PHST- 2017/08/22 06:00 [medline]
PHST- 2016/09/20 06:00 [entrez]
AID - S0006-8993(16)30619-9 [pii]
AID - 10.1016/j.brainres.2016.09.011 [doi]
PST - ppublish
SO  - Brain Res. 2016 Nov 1;1650:252-266. doi: 10.1016/j.brainres.2016.09.011. Epub 
      2016 Sep 15.