PMID- 27642318 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160919 LR - 20201001 IS - 1735-0328 (Print) IS - 1726-6890 (Electronic) IS - 1726-6882 (Linking) VI - 15 IP - 2 DP - 2016 Spring TI - Simultaneous Determination of 13 Priority Polycyclic Aromatic Hydrocarbons in Tehran's Tap Water and Water for Injection Samples Using Dispersive Liquid-Liquid Micro Extraction Method and Gas Chromatography-Mass Spectrometry. PG - 475-81 AB - Polycyclic aromatic hydrocarbons (PAHs) are classified as persistent and carcinogenic organic pollutants. PAHs contamination has been reported in water. Many of relevant regulatory bodies such as EU and EPA have regulated the limit levels for PAHs in drinking water. In this study, 13 priority polycyclic aromatic hydrocarbons (PAHs) were determined in tap water samples of Tehran and water for injection. Dispersive liquid-liquid microextraction procedure combined with gas chromatography-mass spectrometry was used for the extraction and determination of PAHs in the samples. Under the optimized conditions, the range of extraction recoveries and relative standard deviations (RSDs) of PAHs in water using internal standard (anthracene-d10) were in the range of 71-90% and 4-16%, respectively. Limit of detection for different PAHs were between 0.03 and 0.1 ngmL(-1). The concentration of PAHs in all tap water as well as water for injection samples were lower than the limit of quantification of PAHs. This is the first study addressing the occurrence of PAHs in water for injection samples in Iran using dispersive liquid-liquid micro extraction procedure combined with gas chromatography-mass spectrometry. FAU - Sadeghi, Ramezan AU - Sadeghi R AD - Toxicology and PharmacologyDepartment,SchoolofPharmacy, ShahidBeheshti University of Medical Sciences, Tehran, Iran. ; Department of Environmental Health Engineering, School of Health, Shahrekord University of Medical sciences, Shahrekord, Iran. FAU - Kobarfard, Farzad AU - Kobarfard F AD - Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran. FAU - Yazdanpanah, Hassan AU - Yazdanpanah H AD - Food Safety Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Toxicology and PharmacologyDepartment,SchoolofPharmacy, ShahidBeheshti University of Medical Sciences, Tehran, Iran. FAU - Eslamizad, Samira AU - Eslamizad S AD - Food Safety Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Toxicology and PharmacologyDepartment,SchoolofPharmacy, ShahidBeheshti University of Medical Sciences, Tehran, Iran. FAU - Bayate, Mitra AU - Bayate M AD - Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. LA - eng PT - Journal Article PL - Netherlands TA - Iran J Pharm Res JT - Iranian journal of pharmaceutical research : IJPR JID - 101208407 PMC - PMC5018275 OTO - NOTNLM OT - GC-MS OT - Iran OT - Polycyclic Aromatic Hydrocarbons (PAHs) OT - Tap water OT - Water for injection EDAT- 2016/09/20 06:00 MHDA- 2016/09/20 06:01 PMCR- 2016/03/01 CRDT- 2016/09/20 06:00 PHST- 2016/09/20 06:00 [entrez] PHST- 2016/09/20 06:00 [pubmed] PHST- 2016/09/20 06:01 [medline] PHST- 2016/03/01 00:00 [pmc-release] AID - ijpr-15-475 [pii] PST - ppublish SO - Iran J Pharm Res. 2016 Spring;15(2):475-81.