PMID- 27642554
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160919
LR  - 20181113
IS  - 2211-5463 (Print)
IS  - 2211-5463 (Electronic)
IS  - 2211-5463 (Linking)
VI  - 6
IP  - 9
DP  - 2016 Sep
TI  - Expression of nephronectin is enhanced by 1alpha,25-dihydroxyvitamin D3.
PG  - 914-8
LID - 10.1002/2211-5463.12085 [doi]
AB  - The extracellular matrix protein nephronectin (Npnt), also called POEM, is 
      considered to play critical roles as an adhesion molecule in development and 
      functions of various tissues, such as the kidneys, liver, and bone. In the 
      present study, we examined the molecular mechanism of Npnt gene expression and 
      found that vitamin D3 (1alpha,25-dihydroxyvitamin D3,VD 3) strongly enhanced Npnt 
      mRNA expression in MC3T3-E1 cells from a mouse osteoblastic cell line. The VD 
      3-induced increase in Npnt expression is both time- and dose-dependent and is 
      mediated by the vitamin D receptor (VDR).
FAU - Hiranuma, Katsuhiro
AU  - Hiranuma K
AD  - Department of Biochemistry School of Dentistry Showa University Tokyo Japan; 
      Department of Perioperative Medicine Division of Anesthesiology School of 
      Dentistry Showa University Tokyo Japan.
FAU - Yamada, Atsushi
AU  - Yamada A
AD  - Department of Biochemistry School of Dentistry Showa University Tokyo Japan.
FAU - Kurosawa, Tamaki
AU  - Kurosawa T
AD  - Department of Biochemistry School of Dentistry Showa University Tokyo Japan.
FAU - Aizawa, Ryo
AU  - Aizawa R
AD  - Department of Biochemistry School of Dentistry Showa University Tokyo Japan; 
      Department of Periodontology School of Dentistry Showa University Tokyo Japan.
FAU - Suzuki, Dai
AU  - Suzuki D
AD  - Department of Biochemistry School of Dentistry Showa University Tokyo Japan.
FAU - Saito, Yoshiro
AU  - Saito Y
AD  - Department of Biochemistry School of Dentistry Showa University Tokyo Japan; 
      Department of Oral and Maxillofacial Surgery School of Dentistry Showa University 
      Tokyo Japan.
FAU - Nagahama, Ryo
AU  - Nagahama R
AD  - Department of Biochemistry School of Dentistry Showa University Tokyo Japan; 
      Department of Orthodontics School of Dentistry Showa University Tokyo Japan.
FAU - Ikehata, Mikiko
AU  - Ikehata M
AD  - Department of Biochemistry School of Dentistry Showa University Tokyo Japan; 
      Department of Oral and Maxillofacial Surgery Tokyo Medical University Japan.
FAU - Tsukasaki, Masayuki
AU  - Tsukasaki M
AD  - Department of Biochemistry School of Dentistry Showa University Tokyo Japan; 
      Present address: Department of Immunology Graduate School of Medicine and Faculty 
      of Medicine The University of Tokyo Hongo 7-3-1, Bunkyo-ku Tokyo 113-0033 Japan.
FAU - Morimura, Naoko
AU  - Morimura N
AD  - Brain Science Laboratory The Research Organization of Science and Technology 
      Ritsumeikan University Kusatsu Shiga Japan.
FAU - Chikazu, Daichi
AU  - Chikazu D
AD  - Department of Oral and Maxillofacial Surgery Tokyo Medical University Japan.
FAU - Maki, Koutaro
AU  - Maki K
AD  - Department of Orthodontics School of Dentistry Showa University Tokyo Japan.
FAU - Shirota, Tatsuo
AU  - Shirota T
AD  - Department of Oral and Maxillofacial Surgery School of Dentistry Showa University 
      Tokyo Japan.
FAU - Takami, Masamichi
AU  - Takami M
AD  - Department of Pharmacology School of Dentistry Showa University Tokyo Japan.
FAU - Yamamoto, Matsuo
AU  - Yamamoto M
AD  - Department of Periodontology School of Dentistry Showa University Tokyo Japan.
FAU - Iijima, Takehiko
AU  - Iijima T
AD  - Department of Perioperative Medicine Division of Anesthesiology School of 
      Dentistry Showa University Tokyo Japan.
FAU - Kamijo, Ryutaro
AU  - Kamijo R
AD  - Department of Biochemistry School of Dentistry Showa University Tokyo Japan.
LA  - eng
PT  - Journal Article
DEP - 20160713
PL  - England
TA  - FEBS Open Bio
JT  - FEBS open bio
JID - 101580716
PMC - PMC5011489
OTO - NOTNLM
OT  - 1alpha,25-dihydroxyvitamin D3
OT  - nephronectin
OT  - vitamin D receptor
EDAT- 2016/09/20 06:00
MHDA- 2016/09/20 06:01
PMCR- 2016/07/13
CRDT- 2016/09/20 06:00
PHST- 2015/10/16 00:00 [received]
PHST- 2016/04/08 00:00 [revised]
PHST- 2016/05/05 00:00 [accepted]
PHST- 2016/09/20 06:00 [entrez]
PHST- 2016/09/20 06:00 [pubmed]
PHST- 2016/09/20 06:01 [medline]
PHST- 2016/07/13 00:00 [pmc-release]
AID - FEB412085 [pii]
AID - 10.1002/2211-5463.12085 [doi]
PST - epublish
SO  - FEBS Open Bio. 2016 Jul 13;6(9):914-8. doi: 10.1002/2211-5463.12085. eCollection 
      2016 Sep.