PMID- 27646327
OWN - NLM
STAT- MEDLINE
DCOM- 20170404
LR  - 20181202
IS  - 1724-6016 (Electronic)
IS  - 1120-6721 (Linking)
VI  - 27
IP  - 2
DP  - 2017 Mar 10
TI  - Spectral versus time-domain OCT in detecting preoperative epiretinal membranes 
      that accompany macular holes.
PG  - 185-189
LID - 10.5301/ejo.5000862 [doi]
AB  - PURPOSE: To compare the sensitivities of spectral-domain optical coherence 
      tomography (SD-OCT) versus time-domain OCT (TD-OCT) in identifying epiretinal 
      membranes (ERM) preoperatively in patients who underwent surgery for 
      full-thickness macular holes (FTMH). METHODS: This is an interventional 
      retrospective case series of 59 eyes diagnosed with FTMHs who underwent 25-G pars 
      plana vitrectomy with internal limiting membrane peeling between 2009 and 2015. 
      Preoperative OCTs were obtained by SD-OCT (Spectralis, Heidelberg, Germany) or 
      TD-OCT (Stratus, Carl Zeiss Meditec, Dublin, CA, USA). Volume scans were reviewed 
      for ERM accompanying the FTMH. This was compared to indocyanine green-negative 
      staining and intraoperative findings of ERM as the gold standard. RESULTS: 
      Baseline characteristics between the SD-OCT and TD-OCT groups were comparable. 
      Mean duration of postoperative follow-up was 41.4 weeks (+/-49.0). Of 59 eyes, 33 
      (55.9%) exhibited an ERM intraoperatively. Four ERMs (SD-OCT group) compared to 
      12 (TD-OCT group) were not visualized on preoperative OCT (p = 0.003). 
      Sensitivity and specificity of SD-OCT in ERM detection was 79% and 100% compared 
      to 14% and 91% for TD-OCT. Visual acuity improved in both arms (0.5 and 0.3 
      logMAR units in SD-OCT and TD-OCT, respectively (p = 0.002, 0.0002). CONCLUSIONS: 
      We found that SD-OCT was superior to TD-OCT in identifying the presence of ERM 
      preoperatively in patients who underwent macular hole surgery. Since ERMs may 
      decrease the chance of successful pharmacologic vitreolysis, we recommend using 
      SD-OCT over TD-OCT in the evaluation of patients with FTMH to more accurately 
      identify ERMs and allow more comprehensive treatment decisions (pharmacologic 
      versus surgical).
FAU - Rao, Prethy
AU  - Rao P
AD  -  Department of Ophthalmology, Beaumont Eye Institute, Royal Oak, MI - USA.
FAU - Yonekawa, Yoshihiro
AU  - Yonekawa Y
AD  -  Department of Ophthalmology, Beaumont Eye Institute, Royal Oak, MI - USA.
AD  -  Associated Retinal Consultants, Royal Oak, MI - USA.
FAU - Thomas, Benjamin J
AU  - Thomas BJ
AD  -  Department of Ophthalmology, Beaumont Eye Institute, Royal Oak, MI - USA.
AD  -  Associated Retinal Consultants, Royal Oak, MI - USA.
FAU - Drenser, Kimberly A
AU  - Drenser KA
AD  -  Department of Ophthalmology, Beaumont Eye Institute, Royal Oak, MI - USA.
AD  -  Associated Retinal Consultants, Royal Oak, MI - USA.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20160917
PL  - United States
TA  - Eur J Ophthalmol
JT  - European journal of ophthalmology
JID - 9110772
RN  - 0 (Coloring Agents)
RN  - IX6J1063HV (Indocyanine Green)
SB  - IM
MH  - Aged
MH  - Coloring Agents/administration & dosage
MH  - Epiretinal Membrane/*diagnosis/surgery
MH  - Female
MH  - Germany
MH  - Humans
MH  - Indocyanine Green/administration & dosage
MH  - Male
MH  - Middle Aged
MH  - Retinal Perforations/*diagnosis/surgery
MH  - Retrospective Studies
MH  - Sensitivity and Specificity
MH  - Tomography, Optical Coherence/*methods
MH  - Visual Acuity/physiology
MH  - Vitrectomy
EDAT- 2016/10/30 06:00
MHDA- 2017/04/05 06:00
CRDT- 2016/09/21 06:00
PHST- 2016/08/01 00:00 [accepted]
PHST- 2016/10/30 06:00 [pubmed]
PHST- 2017/04/05 06:00 [medline]
PHST- 2016/09/21 06:00 [entrez]
AID - 1275C8D1-CD61-48D0-9242-44052E434E2B [pii]
AID - 10.5301/ejo.5000862 [doi]
PST - ppublish
SO  - Eur J Ophthalmol. 2017 Mar 10;27(2):185-189. doi: 10.5301/ejo.5000862. Epub 2016 
      Sep 17.