PMID- 27647364
OWN - NLM
STAT- MEDLINE
DCOM- 20170818
LR  - 20220410
IS  - 1613-7671 (Electronic)
IS  - 0043-5325 (Linking)
VI  - 128
IP  - Suppl 8
DP  - 2016 Dec
TI  - The accuracy of combined use of troponin and red cell distribution width in 
      predicting mortality of patients with acute pulmonary embolism.
PG  - 596-603
LID - 10.1007/s00508-016-1081-y [doi]
AB  - BACKGROUND: Cardiac troponins and red cell distribution width (RDW) are 
      associated with increased mortality in acute pulmonary embolism (PE). In this 
      study, we aimed to investigate the accuracy of the combined use of troponin and 
      RDW in predicting short-term mortality in acute PE patients. METHODS: The data of 
      201 patients with the diagnosis of acute PE were retrospectively analyzed. We 
      obtained troponin-RDW scores (TR scores) using a combination of troponin and RDW 
      values, and then evaluated this score's accuracy in predicting mortality in 
      patients with acute PE. RESULTS: The mean participant age was 68 +/- 16 years, and 
      52 % of patients were female. Fifteen (7.4 %) patients died during the first 
      month. Patients classified as high-risk according to TR scores were older (72 +/- 
      15 vs. 66 +/- 15 years, p = 0.005), and they had higher heart rates (101 +/- 20 vs. 
      90 +/- 15 beat/min, p < 0.001) and respiratory rates (23 +/- 4 vs. 21 +/- 3 breath/min, 
      p = 0.001). In multivariate analysis, TR (odds ratio [OR] 4.93, 95 % confidence 
      interval [CI] 1.13-21.38, p = 0.033) and simplified pulmonary embolism severity 
      index (sPESI) scores (OR 3.78, 95 % CI 1.71-8.37, p = 0.002) were independent 
      predictors of 30-day mortality. For 30-day mortality, the TR score had a slightly 
      lower sensitivity (87 % vs. 93 %), but a higher specificity (69 % vs. 52 %) 
      compared to the sPESI score. CONCLUSION: The TR score is easy to calculate, and 
      it may be used to predict early mortality in patients with acute PE.
FAU - Yazici, Selcuk
AU  - Yazici S
AD  - Cardiology Clinic, Dr.Siyami Ersek Thoracic and Cardiovascular Surgery Center, 
      Istanbul, Turkey. dr.selcuk75@gmail.com.
AD  - , Cihadiye Street, No: 61/10 A-Blok, 34840, Altintepe, Maltepe-Istanbul, Turkey. 
      dr.selcuk75@gmail.com.
FAU - Kiris, Tuncay
AU  - Kiris T
AD  - Ataturk Training and Research Hospital, Cardiology Clinic, Katip Celebi 
      University, Izmir, Turkey.
FAU - Ceylan, Ufuk S
AU  - Ceylan US
AD  - Cardiology Clinic, Dr.Siyami Ersek Thoracic and Cardiovascular Surgery Center, 
      Istanbul, Turkey.
FAU - Akyuz, Sukru
AU  - Akyuz S
AD  - Cardiology Clinic, Dr.Siyami Ersek Thoracic and Cardiovascular Surgery Center, 
      Istanbul, Turkey.
FAU - Uzun, Ahmet O
AU  - Uzun AO
AD  - Cardiology Clinic, Dr.Siyami Ersek Thoracic and Cardiovascular Surgery Center, 
      Istanbul, Turkey.
FAU - Haci, Recep
AU  - Haci R
AD  - Cardiology Clinic, Dr.Siyami Ersek Thoracic and Cardiovascular Surgery Center, 
      Istanbul, Turkey.
FAU - Terzi, Sait
AU  - Terzi S
AD  - Cardiology Clinic, Dr.Siyami Ersek Thoracic and Cardiovascular Surgery Center, 
      Istanbul, Turkey.
FAU - Dogan, Abdullah
AU  - Dogan A
AD  - Medical School, Izmir Katip Celebi University, Izmir, Turkey.
FAU - Emre, Ayse
AU  - Emre A
AD  - Cardiology Clinic, Dr.Siyami Ersek Thoracic and Cardiovascular Surgery Center, 
      Istanbul, Turkey.
FAU - Yesilcimen, Kemal
AU  - Yesilcimen K
AD  - Cardiology Clinic, Dr.Siyami Ersek Thoracic and Cardiovascular Surgery Center, 
      Istanbul, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20160919
PL  - Austria
TA  - Wien Klin Wochenschr
JT  - Wiener klinische Wochenschrift
JID - 21620870R
RN  - 0 (Troponin)
SB  - IM
MH  - Acute Disease
MH  - Aged
MH  - Erythrocyte Count/*statistics & numerical data
MH  - *Erythrocyte Indices
MH  - Female
MH  - Humans
MH  - Lung Diseases/*blood/diagnosis/*mortality
MH  - Male
MH  - Prevalence
MH  - Prognosis
MH  - Reproducibility of Results
MH  - Risk Assessment/methods
MH  - Sensitivity and Specificity
MH  - *Survival Analysis
MH  - Troponin/*blood
MH  - Turkey/epidemiology
OTO - NOTNLM
OT  - Acute pulmonary embolism
OT  - Red cell distribution width
OT  - SPESI score
OT  - Short-term mortality
OT  - TR score
EDAT- 2016/09/21 06:00
MHDA- 2017/08/19 06:00
CRDT- 2016/09/21 06:00
PHST- 2016/06/02 00:00 [received]
PHST- 2016/08/17 00:00 [accepted]
PHST- 2016/09/21 06:00 [pubmed]
PHST- 2017/08/19 06:00 [medline]
PHST- 2016/09/21 06:00 [entrez]
AID - 10.1007/s00508-016-1081-y [pii]
AID - 10.1007/s00508-016-1081-y [doi]
PST - ppublish
SO  - Wien Klin Wochenschr. 2016 Dec;128(Suppl 8):596-603. doi: 
      10.1007/s00508-016-1081-y. Epub 2016 Sep 19.