PMID- 27649859
OWN - NLM
STAT- MEDLINE
DCOM- 20170123
LR  - 20220310
IS  - 1715-5320 (Electronic)
IS  - 1715-5312 (Linking)
VI  - 41
IP  - 10
DP  - 2016 Oct
TI  - Exercise prescription to reverse frailty.
PG  - 1112-1116
AB  - Frailty is a clinical geriatric syndrome caused by physiological deficits across 
      multiple systems. These deficits make it challenging to sustain homeostasis 
      required for the demands of everyday life. Exercise is likely the best therapy to 
      reverse frailty status. Literature to date suggests that pre-frail older adults, 
      those with 1-2 deficits on the Cardiovascular Health Study-Frailty Phenotype 
      (CHS-frailty phenotype), should exercise 2-3 times a week, for 45-60 min. 
      Aerobic, resistance, flexibility, and balance training components should be 
      incorporated but resistance and balance activities should be emphasized. On the 
      other hand, frail (CHS-frailty phenotype >/= 3 physical deficits) older adults 
      should exercise 3 times per week, for 30-45 min for each session with an emphasis 
      on aerobic training. During aerobic, balance, and flexibility training, both 
      frail and pre-frail older adults should work at an intensity equivalent to a 
      rating of perceived exertion of 3-4 ("somewhat hard") on the Borg CR10 scale. 
      Resistance-training intensity should be based on a percentage of 1-repetition 
      estimated maximum (1RM). Program onset should occur at 55% of 1RM (endurance) and 
      progress to higher intensities of 80% of 1RM (strength) to maximize functional 
      gains. Exercise is the medicine to reverse or mitigate frailty, preserve quality 
      of life, and restore independent functioning in older adults at risk of frailty.
FAU - Bray, Nick W
AU  - Bray NW
AD  - School of Health and Exercise Sciences, University of British Columbia Okanagan, 
      Kelowna, BC V1V 1V7, Canada.
AD  - School of Health and Exercise Sciences, University of British Columbia Okanagan, 
      Kelowna, BC V1V 1V7, Canada.
FAU - Smart, Rowan R
AU  - Smart RR
AD  - School of Health and Exercise Sciences, University of British Columbia Okanagan, 
      Kelowna, BC V1V 1V7, Canada.
AD  - School of Health and Exercise Sciences, University of British Columbia Okanagan, 
      Kelowna, BC V1V 1V7, Canada.
FAU - Jakobi, Jennifer M
AU  - Jakobi JM
AD  - School of Health and Exercise Sciences, University of British Columbia Okanagan, 
      Kelowna, BC V1V 1V7, Canada.
AD  - School of Health and Exercise Sciences, University of British Columbia Okanagan, 
      Kelowna, BC V1V 1V7, Canada.
FAU - Jones, Gareth R
AU  - Jones GR
AD  - School of Health and Exercise Sciences, University of British Columbia Okanagan, 
      Kelowna, BC V1V 1V7, Canada.
AD  - School of Health and Exercise Sciences, University of British Columbia Okanagan, 
      Kelowna, BC V1V 1V7, Canada.
LA  - eng
PT  - Journal Article
DEP - 20160921
PL  - Canada
TA  - Appl Physiol Nutr Metab
JT  - Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition 
      et metabolisme
JID - 101264333
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - *Aging
MH  - *Evidence-Based Medicine
MH  - *Exercise
MH  - *Frail Elderly
MH  - Geriatric Assessment
MH  - *Healthy Lifestyle
MH  - Humans
MH  - *Independent Living
MH  - Physical Exertion
MH  - Physical Fitness
MH  - Postural Balance
MH  - Practice Guidelines as Topic
MH  - *Quality of Life
MH  - Range of Motion, Articular
MH  - Resistance Training
MH  - Sensation Disorders/prevention & control/therapy
MH  - Terminology as Topic
MH  - Time Factors
OTO - NOTNLM
OT  - aging
OT  - entrainement physique
OT  - exercice contre resistance
OT  - exercise prescription
OT  - exercise recommendations
OT  - exercise training
OT  - fragilite
OT  - frailty
OT  - prescription d'exercice
OT  - recommandations en matiere d'exercice physique
OT  - resistance exercise
OT  - vieillissement
EDAT- 2016/09/22 06:00
MHDA- 2017/01/24 06:00
CRDT- 2016/09/22 06:00
PHST- 2016/09/22 06:00 [pubmed]
PHST- 2017/01/24 06:00 [medline]
PHST- 2016/09/22 06:00 [entrez]
AID - 10.1139/apnm-2016-0226 [doi]
PST - ppublish
SO  - Appl Physiol Nutr Metab. 2016 Oct;41(10):1112-1116. doi: 10.1139/apnm-2016-0226. 
      Epub 2016 Sep 21.